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Transfusion reaction and drugs of ingredients of tofacitinib - a phase IV clinical study of FDA data


Summary:

Transfusion reaction is reported only by a few people who take drugs with ingredients of tofacitinib. This phase IV clinical study analyzes 3,343 people who have side effects while taking drugs with ingredients of tofacitinib from the the FDA. Among them, 2 have Transfusion reaction. Find out below who they are, when they have Transfusion reaction and more.

Drug(s) considered in the study (i.e. both brand name and generic drugs): Tofacitinib.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Feb, 07, 2023

3,343 people reported to have side effects when taking drugs with ingredients of tofacitinib.
Among them, 2 people (0.06%) have Transfusion reaction

What is Transfusion reaction?

Transfusion reaction (a serious problem that occurs after a patient receives a transfusion of blood) is found to be associated with 699 drugs and 354 conditions by eHealthMe.

Number of reports submitted per year:

Could drugs with ingredients of tofacitinib cause Transfusion reaction?

Gender of people who have Transfusion reaction when taking drugs with ingredients of tofacitinib *:

  • female: 100 %
  • male: 0.0 %

Age of people who have Transfusion reaction when taking drugs with ingredients of tofacitinib *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 100 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

Other drugs people take *:

  1. Vitamin D: 2 people, 100.00%
  2. Simponi: 2 people, 100.00%
  3. Methotrexate: 2 people, 100.00%
  4. Folic Acid: 2 people, 100.00%
  5. Calcium: 2 people, 100.00%
  6. Humira: 1 person, 50.00%
  7. Acetaminophen: 1 person, 50.00%

Other side effects people have besides Transfusion reaction *:

  1. Tinnitus (a ringing in the ears): 2 people, 100.00%
  2. Synovitis (inflammation of the synovial membrane): 2 people, 100.00%
  3. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 100.00%
  4. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 100.00%
  5. Drug Intolerance (drug sensitivity): 2 people, 100.00%
  6. Drug Ineffective: 2 people, 100.00%
  7. C-Reactive Protein Decreased: 2 people, 100.00%
  8. Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death): 2 people, 100.00%

* Approximation only. Some reports may have incomplete information.

How to use the study?

You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood.

Related studies

Drugs with ingredients of tofacitinib, their effectiveness, alternatives and more:

How the study uses the data?

The study uses data from the FDA. It is based on tofacitinib. All drugs that have the same active ingredients (e.g. brand name and generic drugs) are considered. Dosage of drugs is not considered in the study.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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