Moderna COVID Vaccine and Hypertensive encephalopathy - a phase IV clinical study of CDC and FDA data


Hypertensive encephalopathy is reported only by a few people who get Moderna COVID Vaccine.

The phase IV clinical study analyzes which people get Moderna COVID Vaccine and have Hypertensive encephalopathy. It is created by eHealthMe based on reports of 297,825 people who have side effects while getting Moderna COVID Vaccine from the CDC and the FDA, and is updated regularly.

With medical big data and AI algorithms, eHealthMe enables everyone to run phase IV clinical trial to detect adverse drug outcomes and monitor effectiveness. Our original studies have been referenced on 600+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Most recently, phase IV clinial trails for COVID 19 vaccines have been added, check here.

On Jul, 14, 2022

297,825 people reported to have side effects after getting Moderna COVID Vaccine.
Among them, 3 people (0.0%) have Hypertensive encephalopathy.

What is Hypertensive encephalopathy?

Hypertensive encephalopathy (neurological dysfunction induced by malignant hypertension) is found to be associated with 427 drugs and 235 conditions by eHealthMe.

Number of reports submitted per year:

Moderna covid vaccine and Hypertensive encephalopathy?

Time to have Hypertensive encephalopathy from when people get Moderna COVID Vaccine *:

  • on the same day: 33.33 %
  • in the first week: 66.67 %
  • in the first 30 days: 0.0 %
  • after 30 days: 0.0 %

Gender of people *:

  • female: 66.67 %
  • male: 33.33 %

Age of people *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 33.33 %
  • 50-59: 0.0 %
  • 60+: 66.67 %

Did people recover *:

  • yes: 100 %
  • no: 0.0 %

Death as an outcome *:

  • yes: 0.0 %
  • no: 100 %

# of vaccine dose *:

  • 1: 33.33 %
  • 2: 66.67 %
  • 3+: 0.0 %

Common side effects people have besides Hypertensive encephalopathy *:

  1. High Blood Pressure: 3 people, 100.00%
  2. Posterior Reversible Encephalopathy Syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss): 2 people, 66.67%
  3. Confusional State: 2 people, 66.67%
  4. Feeling Abnormal: 2 people, 66.67%
  5. Weakness: 1 person, 33.33%
  6. Fatigue (feeling of tiredness): 1 person, 33.33%
  7. Balance Disorder: 1 person, 33.33%
  8. Blood Creatinine Increased: 1 person, 33.33%
  9. Blood Pressure Systolic Increased: 1 person, 33.33%
  10. Brain Oedema (excess accumulation of fluid in the intracellular or extracellular spaces of the brain): 1 person, 33.33%

* Approximation only. Some reports may have incomplete information.

Related studies

Other COVID vaccine studies:

Vaccine side effects by duration, gender, age and dose:

Common Moderna covid vaccine side effects:

Browse all side effects of Moderna COVID Vaccine:

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How the study uses the data?

The study is based on data from the CDC and the FDA.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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