Pfizer BioNTech Covid Vaccine and Antiphospholipid antibodies positive - a phase IV clinical study of CDC and FDA data


Antiphospholipid antibodies positive is found among people who get Pfizer BioNTech Covid Vaccine, especially for people who are female, 30-39 old, and in the first 30 days of getting the vaccine.

The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Antiphospholipid antibodies positive. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. You can use the study as a second opinion to make health care decisions.

Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature.

On Mar, 22, 2023

401,887 people reported to have side effects after getting Pfizer BioNTech Covid Vaccine.
Among them, 11 people (0.0%) have Antiphospholipid antibodies positive.

What is Antiphospholipid antibodies positive?

Antiphospholipid antibodies positive is found to be associated with 460 drugs and 269 conditions by eHealthMe.

Number of reports submitted per year:

Pfizer biontech covid vaccine and Antiphospholipid antibodies positive?

Time to have Antiphospholipid antibodies positive from when people get Pfizer BioNTech Covid Vaccine *:

  • on the same day: 20 %
  • in the first week: 20 %
  • in the first 30 days: 50 %
  • after 30 days: 10 %

Gender of people *:

  • female: 72.73 %
  • male: 27.27 %

Age of people *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 11.11 %
  • 20-29: 0.0 %
  • 30-39: 44.44 %
  • 40-49: 11.11 %
  • 50-59: 11.11 %
  • 60+: 22.22 %

Did people recover *:

  • yes: 30 %
  • no: 70 %

Death as an outcome *:

  • yes: 0.0 %
  • no: 100 %

# of vaccine dose *:

  • 1: 40 %
  • 2: 50 %
  • 3+: 10 %

Common side effects people have besides Antiphospholipid antibodies positive *:

  1. Pain: 3 people, 27.27%
  2. Activated Partial Thromboplastin Time Prolonged: 3 people, 27.27%
  3. Joint Pain: 3 people, 27.27%
  4. Pain In Extremity: 2 people, 18.18%
  5. Antiphospholipid Syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss): 2 people, 18.18%
  6. Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 18.18%
  7. Inflammation: 2 people, 18.18%
  8. Muscle Spasms (muscle contraction): 2 people, 18.18%
  9. Pulmonary Embolism (blockage of the main artery of the lung): 2 people, 18.18%
  10. Antinuclear Antibody Positive: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Related studies

Other COVID vaccine studies:

Vaccine side effects by duration, gender, age and dose:

Common Pfizer biontech covid vaccine side effects:

Browse all side effects of Pfizer BioNTech Covid Vaccine:

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How the study uses the data?

The study is based on data from the CDC and the FDA.

Who is eHealthMe?

With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).


WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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