How effective is Desyrel for Bipolar 1 (Bipolar i disorder)? (a real world drug study)

Summary:

Overall ratings: 2.8/5
Long term ratings: 2.3/5

This is a phase IV clinical study of how effective Desyrel (trazodone hydrochloride) is for Bipolar 1 and for what kind of people. The study is created by eHealthMe from 5 Desyrel users and is updated continuously.

What is Desyrel?

Desyrel has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 6,595 Desyrel users. Check the latest studies of Desyrel.

What is Bipolar 1?

Bipolar 1 (mood disorder that is characterized by at least one manic or mixed episode) is found to be associated with 432 drugs and 831 conditions by eHealthMe. Check the latest studies of Bipolar 1.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.


On Aug, 23, 2026

5 people are studied for taking Desyrel in Bipolar 1

Overall effectiveness (number of people):

Does Desyrel work for your Bipolar 1 (overall)?

Long term (1+ years) effectiveness (number of people):

Does Desyrel work for your Bipolar 1 (long term)?

Desyrel effectiveness for Bipolar 1 (number of people):

Overall:
  • not at all: 0
  • somewhat: 3
  • moderate: 1
  • high: 0
  • very high: 1
Long Term:
  • not at all: 0
  • somewhat: 2
  • moderate: 1
  • high: 0
  • very high: 0

Gender of people who take Desyrel for Bipolar 1 *:

  • female: 100 %
  • male: 0.0 %

Age of people who take Desyrel for Bipolar 1 *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 20 %
  • 40-49: 60 %
  • 50-59: 20 %
  • 60+: 0.0 %

Who find Desyrel more effective for Bipolar 1?

Gender of people who take Desyrel for Bipolar 1 *:

  • female: 100 %
  • male: 0.0 %

Age of people who take Desyrel for Bipolar 1 *:

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 100 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 0.0 %

* Approximation only. Some reports may have incomplete information.

Do you take Desyrel?

- You can start a phase IV clinical trial to monitor Desyrel safety and effectiveness.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Related studies

Alternative drugs to, pros and cons of:

Treatments, associated drugs and conditions:

How the study uses the data?

The study is based on trazodone hydrochloride (the active ingredients of Desyrel) and Desyrel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study neither.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: