Reglan Vs. Linzess for a female patient aged 48 (an AI-powered real world drug study)
Summary:
This is a personalized comparison of Reglan, Linzess for a woman aged 48. The study is created by eHealthMe based on reports from the FDA and eHealthme.
9,372 females aged 48 (±5) who take Reglan, Linzess and have adverse effects are studied.
Number of reports submitted per year:
Information of the patient in this study:
- Age: 48
- Gender: female
What are the drugs?
- Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
- Linzess has active ingredients of linaclotide. It is often used in constipation. eHealthMe is studying from 24,086 Linzess users. Check the latest studies of Linzess.
What is the reason to compare the drugs?
- Impaction of the bowels is found to be associated with 3 conditions by eHealthMe. Check the latest studies of Impaction of the bowels.
What are the adverse effects to be compared?
- Constipation is found to be associated with 3,003 drugs and 4,602 conditions by eHealthMe. Check the latest studies of Constipation.
- Gastroparesis: no further information found. Check the latest studies of Gastroparesis.
- Inflammation is found to be associated with 1,707 drugs and 1,873 conditions by eHealthMe. Check the latest studies of Inflammation.
eHealthMe real world results:
Comparison with the specified adverse outcomes (outcome and its % of total reports):
Constipation:
- Reglan: 2.97 %
- Linzess: 1.1 %
Gastroparesis (delayed emptying of food from the stomach):
- Reglan: 0.0 %
- Linzess: 0.0 %
Inflammation:
- Reglan: 0.46 %
- Linzess: 0.09 %
Most common side effects:
Reglan:
- Vomiting
- Dyspnoea (difficult or laboured respiration)
- Pyrexia (fever)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Pain
- Abdominal Pain
- Anxiety
- Headache (pain in head)
- Rash
Linzess:
- Diarrhoea
- Headache (pain in head)
- Drug Ineffective
- Fatigue (feeling of tiredness)
- Pain
- Anxiety
- Dizziness
- Abdominal Pain
- Depression
- Abdominal Distension
Most common side effects experienced by people in long term (1+ years) use:
Reglan:
- Tardive Dyskinesia (a disorder that involves involuntary movements)
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck)
- Back Pain
- Anxiety
- Emotional Disorder
- Peripheral Swelling
- Deep Vein Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Joint Swelling
- Swelling Face
- Dyskinesia (abnormality or impairment of voluntary movement)
Linzess:
- Pain
- Diarrhoea
- Weight Gain
- Rash
- Burning Sensation
- Cervical Radiculopathy (disturbance of nerve function that causes pain in the upper body)
- Drug Hypersensitivity
- Drug Ineffective
- Dysuria (painful or difficult urination)
- Enuresis (repeated inability to control urination)
Drug effectiveness:
Reglan:
- not at all: 6.25 %
- somewhat: 38.75 %
- moderate: 30.0 %
- high: 17.5 %
- very high: 7.5 %
Linzess:
- not at all: 5.8 %
- somewhat: 23.19 %
- moderate: 23.19 %
- high: 30.43 %
- very high: 17.39 %
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
Related studies
- Reglan side effects in long term, by gender and age (28,866 reports)
- Linzess side effects in long term, by gender and age (23,564 reports)
How the study uses the data?
The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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