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Fioricet Vs. Maxalt for a male patient aged 65 (an AI-powered real world drug study)

Summary:

This is a personalized comparison of Fioricet, Maxalt for a man aged 65. The study is created by eHealthMe based on reports from the FDA and eHealthme.

On Jul, 25, 2026

4,431 males aged 65 (±5) who take Fioricet, Maxalt and have adverse effects are studied.

Number of reports submitted per year:

Fioricet, Maxalt for a male patient aged 65.

Information of the patient in this study:

  • Age: 65
  • Gender: male

What are the drugs?

  • Fioricet has active ingredients of acetaminophen; butalbital; caffeine. It is often used in migraine. eHealthMe is studying from 12,423 Fioricet users. Check the latest studies of Fioricet.
  • Maxalt has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 12,754 Maxalt users. Check the latest studies of Maxalt.

What is the reason to compare the drugs?

What are the adverse effects to be compared?

eHealthMe real world results:

Comparison with the specified adverse outcomes (outcome and its % of total reports):

Migraine (headache):

  • Fioricet: 0.81 %
  • Maxalt: 0.27 %

Most common side effects:

Fioricet:

  1. Pyrexia (fever)
  2. Dyspnoea (difficult or laboured respiration)
  3. Fatigue (feeling of tiredness)
  4. Pneumonia
  5. Drug Ineffective
  6. Blood Pressure Increased
  7. Death
  8. Chronic Kidney Disease
  9. Diarrhoea
  10. Pain

Maxalt:

  1. Fatigue (feeling of tiredness)
  2. Pain
  3. Dizziness
  4. Drug Ineffective
  5. Dyspnoea (difficult or laboured respiration)
  6. Asthenia (weakness)
  7. Anxiety
  8. Nausea (feeling of having an urge to vomit)
  9. Death
  10. Back Pain

Most common side effects experienced by people in long term (1+ years) use:

Fioricet:

  1. Chronic Kidney Disease
  2. Renal Failure (kidney dysfunction)
  3. Weight Decreased
  4. Pain
  5. Blood Pressure Increased
  6. Heart Rate Decreased
  7. Hypotension (abnormally low blood pressure)
  8. Malaise (a feeling of general discomfort or uneasiness)
  9. Pneumonia
  10. Drug Ineffective

Maxalt:

  1. Jitters (to make someone nervous or frightened)
  2. Anemia (less than the normal quantity of haemoglobin in the blood)

Drug effectiveness:

Fioricet:

  • not at all: 0 %
  • somewhat: 11.11 %
  • moderate: 11.11 %
  • high: 66.67 %
  • very high: 11.11 %

Maxalt:

  • not at all: 0 %
  • somewhat: 0 %
  • moderate: 20 %
  • high: 60 %
  • very high: 20 %


How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

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How the study uses the data?

The study is based on gender, age, active ingredients of any drugs used. Other drugs that have the same active ingredients (e.g. generic drugs) are considered. Dosage of drugs is not considered in the study.

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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