Accolate and Aerobid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accolate (zafirlukast) and Aerobid (flunisolide). Common drug interactions include mitral valve incompetence among females and appetite increased among males.

The phase IV clinical study analyzes what interactions people have when they take Accolate and Aerobid. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Accolate?

Accolate has active ingredients of zafirlukast. It is often used in asthma. eHealthMe is studying from 4,220 Accolate users. Check the latest studies of Accolate.

What is Aerobid?

Aerobid has active ingredients of flunisolide. eHealthMe is studying from 1,126 Aerobid users. Check the latest studies of Aerobid.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

44 people who take Accolate and Aerobid together, and have interactions are studied.

What are the common drug interactions of Accolate and Aerobid, by gender? *:

female:

Mitral valve incompetence (inefficient heart valve)
Myelitis (infection or the inflammation of white matter or gray matter of spinal cord which is a part of central nervous system)
Neck pain
Necrosis (the death of body tissue)
Nervousness
Otitis externa (external ear infection)
Otitis media (inflammation of the middle ear)
Pain
Pain in limb
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)

male:

Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Blood creatine phosphokinase increased
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Asthenia (weakness)
Balance disorder
Cardiac arrest
Cough
Deafness transitory (deafness temporary)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diplopia (double vision)

What are the common drug interactions of Accolate and Aerobid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Pruritus (severe itching of the skin)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Weight decreased

20-29:

Arrhythmia (irregular heartbeat)
Cardiac arrest
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Drug ineffective
Status asthmaticus (a asthma attack not responds to regular medicines)
Vomiting
Acute respiratory failure
Breath sounds decreased
Cough
Pulmonary congestion (congestion in the lungs)

30-39:

n/a

40-49:

Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Syncope (loss of consciousness with an inability to maintain postural tone)
Unevaluable reaction
Wegener's granulomatosis (inflammation of the blood vessels lungs sinuses)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Blood albumin decreased
Blood alkaline phosphatase nos increased
Blood creatine phosphokinase increased
Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

50-59:

Sweating increased (excess sweating)
Breast pain
Night sweats (sweating in night)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Back pain
Cardiomegaly (increased size of heart than normal)
Cardiomyopathy (weakening of the heart muscle)
Chest pain
Churg strauss syndrome (infection of small arteries and vein)
Cough

60+:

Alopecia (absence of hair from areas of the body)
Blood creatine phosphokinase increased
Abdominal discomfort
Anaemia (lack of blood)
Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Arrhythmia (irregular heartbeat)
Asthenia (weakness)
Balance disorder
Blood in stool
Cardiac arrest

* Approximation only. Some reports may have incomplete information.

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