Accupril and Trusopt drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accupril (quinapril hydrochloride) and Trusopt (dorzolamide hydrochloride). Common drug interactions include deafness among females and dyskinesia among males.

The phase IV clinical study analyzes what interactions people have when they take Accupril and Trusopt. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Accupril?

Accupril has active ingredients of quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 13,404 Accupril users. Check the latest studies of Accupril.

What is Trusopt?

Trusopt has active ingredients of dorzolamide hydrochloride. It is often used in glaucoma. eHealthMe is studying from 3,165 Trusopt users. Check the latest studies of Trusopt.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

18 people who take Accupril and Trusopt together, and have interactions are studied.

What are the common drug interactions of Accupril and Trusopt, by gender? *:

female:

Deafness
Diarrhoea
Haemorrhage (bleeding)
Hyperkalaemia (damage to or disease of the kidney)
Hypokalaemia (low potassium)
Infection
Nausea (feeling of having an urge to vomit)
Procedural hypotension
Alopecia (absence of hair from areas of the body)
Arthropathy

male:

Dyskinesia (abnormality or impairment of voluntary movement)
Hypokinesia (decreased bodily movement)
Dysphagia (a condition in which swallowing is difficult or painful)
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch)
Muscular weakness (muscle weakness)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Pain
Pain in extremity
Paralysis
Tendon disorder (disease of tendon)

What are the common drug interactions of Accupril and Trusopt, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Diarrhoea
Nausea (feeling of having an urge to vomit)
Convulsions (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled of muscles contract and relax rapidly and repeatedly)

60+:

Deafness
Dyskinesia (abnormality or impairment of voluntary movement)
Anaemia (lack of blood)
Aortic stenosis (obstruction to the outflow of blood from the left ventricle into the aorta)
Arthropathy
Asthenia (weakness)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Cardiac flutter (abnormal heart rhythm)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

What are the existing conditions these people have? *

Pain: 2 people, 11.11%
Diabetes: 2 people, 11.11%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 1 person, 5.56%
Multiple Myeloma (cancer of the plasma cells): 1 person, 5.56%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.56%
Asthma: 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

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