Accuretic and Hydrochlorothiazide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accuretic (hydrochlorothiazide; quinapril hydrochloride) and Hydrochlorothiazide (hydrochlorothiazide). Common drug interactions include limb discomfort among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Accuretic and Hydrochlorothiazide. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Accuretic?

Accuretic has active ingredients of hydrochlorothiazide; quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,106 Accuretic users. Check the latest studies of Accuretic.

What is Hydrochlorothiazide?

Hydrochlorothiazide has active ingredients of hydrochlorothiazide. It is often used in high blood pressure. eHealthMe is studying from 182,194 Hydrochlorothiazide users. Check the latest studies of Hydrochlorothiazide.

On Jul, 26, 2026

44 people who take Accuretic and Hydrochlorothiazide together, and have interactions are studied.

Accuretic and Hydrochlorothiazide drug interactions.

What are the common drug interactions of Accuretic and Hydrochlorothiazide, by gender? *:

female:

Limb discomfort (discomfort in leg)
Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
Obesity (having too much body fat)
Peripheral swelling
Syncope (loss of consciousness with an inability to maintain postural tone)
Chronic kidney disease
Renal failure (kidney dysfunction)
Nephropathy (damage to or disease of a kidney)
Pemphigoid (tense blisters on the skin)
Back pain

male:

Chronic kidney disease
Renal failure (kidney dysfunction)
Dyspnoea (difficult or laboured respiration)
Dysuria (painful or difficult urination)
Haematuria (presence of blood in urine)
Infection
Oedema (fluid collection in tissue)
Vomiting
Alopecia (absence of hair from areas of the body)
Anger

What are the common drug interactions of Accuretic and Hydrochlorothiazide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Nausea (feeling of having an urge to vomit)
Nystagmus (a condition of involuntary eye movement)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Tremor (trembling or shaking movements in one or more parts of your body)
Vertigo
Vomiting
Balance disorder
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disturbance in attention
Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)

40-49:

Back pain
Chronic kidney disease
Panic attack
Pemphigoid (tense blisters on the skin)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Breast cancer
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Depression
Injection site erythema (redness at injection site)

50-59:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dyspnoea (difficult or laboured respiration)
Abdominal pain
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Cerebrovascular disorder (disease of brain)
Chronic kidney disease
Constipation
Dizziness
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)

60+:

Chronic kidney disease
Renal failure (kidney dysfunction)
Epistaxis (bleed from the nose)
Fatigue (feeling of tiredness)
Hyperkalaemia (damage to or disease of the kidney)
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)
Joint swelling
Local swelling (swelling at the site of some application of substance or injury)
Peripheral swelling

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 31.82%
Pain: 10 people, 22.73%
High Blood Cholesterol: 10 people, 22.73%
Diabetes: 8 people, 18.18%
Stress And Anxiety: 6 people, 13.64%
Cardiac Disorder: 5 people, 11.36%
Depression: 5 people, 11.36%
Quit Smoking: 4 people, 9.09%
Multiple Allergies (allergy to multiple agents): 4 people, 9.09%
Essential Thrombocythaemia (chronic blood cancer): 4 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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