Accuretic and Prilosec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Accuretic (hydrochlorothiazide; quinapril hydrochloride) and Prilosec (omeprazole). Common drug interactions include ankle fracture among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Accuretic and Prilosec. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Accuretic?

Accuretic has active ingredients of hydrochlorothiazide; quinapril hydrochloride. It is often used in high blood pressure. eHealthMe is studying from 1,106 Accuretic users. Check the latest studies of Accuretic.

What is Prilosec?

Prilosec has active ingredients of omeprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 175,286 Prilosec users. Check the latest studies of Prilosec.



On Aug, 06, 2026

24 people who take Accuretic and Prilosec together, and have interactions are studied.

Accuretic and Prilosec drug interactions.

What are the common drug interactions of Accuretic and Prilosec, by gender? *:

female:

  1. Ankle fracture
  2. Asthma
  3. Back pain
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Chest pain
  6. Drug ineffective
  7. Ear infection
  8. Fall
  9. Infusion site haemorrhage (bleeding from infusion site)
  10. Abscess jaw (tooth abscess or root abscess)

male:

  1. Renal failure (kidney dysfunction)
  2. Renal tubular necrosis (death of kidney tubules)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Blood glucose decreased
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Accuretic and Prilosec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Adenomyosis (presence of ectopic glandular tissue found in muscle)
  2. Drug ineffective
  3. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  4. Rectal haemorrhage (bleeding from anus)
  5. Uterine leiomyoma (uterine benign tumour derived from smooth muscle)

40-49:

  1. Anxiety disorder
  2. Arthralgia (joint pain)
  3. Back pain
  4. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  5. Blood cholesterol increased
  6. Chest pain
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Constipation
  9. Depression
  10. Diabetes mellitus inadequate control

50-59:

  1. Abscess jaw (tooth abscess or root abscess)
  2. Arthralgia (joint pain)
  3. Chills (felling of cold)
  4. Device related infection
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diarrhoea
  7. Drug ineffective
  8. Dry mouth
  9. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  10. Haemorrhage (bleeding)

60+:

  1. Chronic kidney disease
  2. Renal injury (kidney injury)
  3. Blood glucose increased
  4. Chest discomfort
  5. Cystitis (inflammation of the wall of the bladder)
  6. Dehydration (dryness resulting from the removal of water)
  7. Infusion site extravasation (flow of (blood or lymph) from infusion site)
  8. Chest pain
  9. Cough
  10. Haemoglobin decreased

What are the existing conditions these people have? *

  1. Primary Immunodeficiency Syndrome: 3 people, 12.50%
  2. Type 2 Diabetes: 2 people, 8.33%
  3. Sinus Disorder (disease of sinus): 2 people, 8.33%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 8.33%
  5. Immune System Disorder: 2 people, 8.33%
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.33%
  7. Hypersensitivity: 2 people, 8.33%
  8. Gastric Disorder (disease of stomach): 2 people, 8.33%
  9. Depression: 2 people, 8.33%
  10. Cardiac Disorder: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Accuretic and Prilosec?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Accuretic and Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Accuretic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prilosec:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Accuretic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prilosec and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on hydrochlorothiazide; quinapril hydrochloride and omeprazole (the active ingredients of Accuretic and Prilosec, respectively), and Accuretic and Prilosec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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