Acephen and Promethegan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acephen (acetaminophen) and Promethegan (promethazine hydrochloride). Common drug interactions include conjunctivitis among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Acephen and Promethegan. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Acephen?
Acephen has active ingredients of acetaminophen. eHealthMe is studying from 91 Acephen users. Check the latest studies of Acephen.
What is Promethegan?
Promethegan has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 428 Promethegan users. Check the latest studies of Promethegan.
14 people who take Acephen and Promethegan together, and have interactions are studied.
What are the common drug interactions of Acephen and Promethegan, by gender? *:
female:
- Conjunctivitis (pink eye)
- Hypersensitivity
- Orbital oedema (swelling of orbit)
- Pneumomediastinum (air is present in the mediastinum)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Subcutaneous emphysema (smooth bulging of the skin)
male:
- Chronic kidney disease
- Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
- Renal tubular necrosis (death of kidney tubules)
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
- Bone metabolism disorder
What are the common drug interactions of Acephen and Promethegan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Chronic kidney disease
- Renal tubular acidosis (medical condition that involves an accumulation of acid in the body due to a failure of the kidneys)
- Conjunctivitis (pink eye)
- Hypersensitivity
- Orbital oedema (swelling of orbit)
- Pneumomediastinum (air is present in the mediastinum)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Renal tubular necrosis (death of kidney tubules)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Subcutaneous emphysema (smooth bulging of the skin)
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 11 people, 78.57%
- Premature Labor: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Acephen and Promethegan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acephen (91 reports)
- Promethegan (428 reports)
Browse all drug interactions of Acephen and Promethegan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acephen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Promethegan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acephen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Promethegan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on acetaminophen and promethazine hydrochloride (the active ingredients of Acephen and Promethegan, respectively), and Acephen and Promethegan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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