Acephen and Prozac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acephen (acetaminophen) and Prozac (fluoxetine hydrochloride). Common drug interactions include anhedonia among females.

The phase IV clinical study analyzes what interactions people have when they take Acephen and Prozac. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Acephen?

Acephen has active ingredients of acetaminophen. eHealthMe is studying from 91 Acephen users. Check the latest studies of Acephen.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.



On Jul, 16, 2026

16 people who take Acephen and Prozac together, and have interactions are studied.

Acephen and Prozac drug interactions.

What are the common drug interactions of Acephen and Prozac, by gender? *:

female:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  3. Hot flush (sudden feelings of heat)
  4. Hydronephrosis (water inside the kidney)
  5. Injury
  6. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
  7. Metastases to bone (cancer spreads to bone)
  8. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pain

male:

n/a

What are the common drug interactions of Acephen and Prozac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Acidosis (build-up of carbon dioxide in the blood)
  2. Anaphylactic reaction (serious allergic reaction)
  3. Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
  4. Bladder neoplasm (bladder tumour)
  5. Bloody discharge
  6. Bone disorder
  7. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  8. Bone pain
  9. Breast calcifications (deposits of calcium that can be seen on a mammogram of the breast)
  10. Breast cancer metastatic

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

  1. Muscle Spasms (muscle contraction): 16 people, 100.00%
  2. Metastases To Bone (cancer spreads to bone): 16 people, 100.00%
  3. Constipation: 16 people, 100.00%
  4. Breast Cancer Metastatic: 16 people, 100.00%
  5. Breast Cancer: 16 people, 100.00%
  6. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Acephen and Prozac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acephen and Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acephen:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acephen and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acetaminophen and fluoxetine hydrochloride (the active ingredients of Acephen and Prozac, respectively), and Acephen and Prozac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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