Acetazolamide and Duphalac drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Duphalac (lactulose). Common drug interactions include anaemia among females and toxic epidermal necrolysis among males.
The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Duphalac. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Acetazolamide?
Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.
What is Duphalac?
Duphalac has active ingredients of lactulose. It is often used in constipation. eHealthMe is studying from 5,152 Duphalac users. Check the latest studies of Duphalac.
13 people who take Acetazolamide and Duphalac together, and have interactions are studied.

What are the common drug interactions of Acetazolamide and Duphalac, by gender? *:
female:
- Anaemia (lack of blood)
- Haemoglobin decreased
- Mitral valve incompetence (inefficient heart valve)
- Oxygen saturation decreased
- Pericardial effusion (fluid around the heart)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
- Arrhythmia (irregular heartbeat)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
male:
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
What are the common drug interactions of Acetazolamide and Duphalac, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Anaemia (lack of blood)
- Haemoglobin decreased
- Mitral valve incompetence (inefficient heart valve)
- Oxygen saturation decreased
- Pericardial effusion (fluid around the heart)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
- Ventricular hypertrophy (enlargement of ventricles (lower chambers) in the heart)
- Arrhythmia (irregular heartbeat)
What are the existing conditions these people have? *
- Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 12 people, 92.31%
- Stress And Anxiety: 12 people, 92.31%
- Sedation: 12 people, 92.31%
- Pneumonia: 12 people, 92.31%
- High Blood Pressure: 12 people, 92.31%
- Fever: 12 people, 92.31%
- Diarrhea: 12 people, 92.31%
- Depression: 12 people, 92.31%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 12 people, 92.31%
- Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 12 people, 92.31%
* Approximation only. Some reports may have incomplete information.
Do you take Acetazolamide and Duphalac?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetazolamide (6,178 reports)
- Duphalac (5,152 reports)
Browse all drug interactions of Acetazolamide and Duphalac:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetazolamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Duphalac:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetazolamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Duphalac and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on acetazolamide and lactulose (the active ingredients of Acetazolamide and Duphalac, respectively), and Acetazolamide and Duphalac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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