Acetazolamide and Thiamine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetazolamide (acetazolamide) and Thiamine (thiamine (vitamin b1)). Common drug interactions include back pain among females and drug hypersensitivity among males.
The phase IV clinical study analyzes what interactions people have when they take Acetazolamide and Thiamine. It is created by eHealthMe based on reports of 61 people who take the same drugs from the FDA, and is updated regularly.
What is Acetazolamide?
Acetazolamide has active ingredients of acetazolamide. It is often used in pseudotumor cerebri. eHealthMe is studying from 6,178 Acetazolamide users. Check the latest studies of Acetazolamide.
What is Thiamine?
Thiamine has active ingredients of thiamine (vitamin b1). eHealthMe is studying from 11,036 Thiamine users. Check the latest studies of Thiamine.
61 people who take Acetazolamide and Thiamine together, and have interactions are studied.

What are the common drug interactions of Acetazolamide and Thiamine, by gender? *:
female:
- Back pain
- Balance disorder
- Cerebral atrophy (decrement in size of brain)
- Erythema (redness of the skin)
- Eyelid disorder
- Fall
- Injection site erythema (redness at injection site)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Injection site pain
- Injection site pruritus (severe itching at injection site)
male:
- Drug hypersensitivity
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Asthenia (weakness)
- Burkholderia test positive
- Cholecystitis acute (rapid infection of gallbladder)
- Death
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Diarrhoea
- Drug ineffective
- Enterobacter pneumonia (lung inflammation caused by bacteria of the family enterobacteriaceae)
What are the common drug interactions of Acetazolamide and Thiamine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
- Enterococcal sepsis
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
20-29:
- Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
- Drug ineffective
30-39:
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Asthenia (weakness)
- Cholecystitis acute (rapid infection of gallbladder)
- Dyspnoea (difficult or laboured respiration)
- Gastrointestinal necrosis (destruction of gastrointestinal organ)
- General physical health deterioration (weak health status)
- Hypercapnia (too much smoke)
- Intestinal perforation (complete penetration of the wall of the intestine)
- Liver disorder (liver diseases)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
40-49:
- Blood pressure increased
- Hepatic failure (liver failure)
50-59:
- Back pain
- Balance disorder
- Cerebral atrophy (decrement in size of brain)
- Erythema (redness of the skin)
- Eyelid disorder
- Fall
- Injection site erythema (redness at injection site)
- Injection site haematoma (localized swelling filled with blood at injection site)
- Injection site pain
- Injection site pruritus (severe itching at injection site)
60+:
- Drug hypersensitivity
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Lower gastrointestinal haemorrhage (bleeding in the large intestine, rectum, or anus is called lower gi bleeding)
- Melaena (the passage of black, tarry stools)
- Oedema peripheral (superficial swelling)
- Oropharyngeal pain
- Pneumonia
- Pneumonia bacterial (pneumonia associated with bacterial infection)
- Pyrexia (fever)
- Sepsis (a severe blood infection that can lead to organ failure and death)
What are the existing conditions these people have? *
- Sedation: 21 people, 34.43%
- Constipation: 19 people, 31.15%
- Stress And Anxiety: 16 people, 26.23%
- High Blood Pressure: 16 people, 26.23%
- Fever: 14 people, 22.95%
- Pneumonia: 11 people, 18.03%
- Diarrhea: 11 people, 18.03%
- Depression: 11 people, 18.03%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 11 people, 18.03%
- Ards (Acute Respiratory Distress Syndrome) (sudden failure of the respiratory (breathing) system): 11 people, 18.03%
* Approximation only. Some reports may have incomplete information.
Do you take Acetazolamide and Thiamine?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetazolamide (6,178 reports)
- Thiamine (11,036 reports)
Browse all drug interactions of Acetazolamide and Thiamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetazolamide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Thiamine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetazolamide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Thiamine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
- Hu CY, Lee BJ, Cheng HF, Wang CY, "Acetazolamide-related life-threatening hypophosphatemia in a glaucoma patient", Journal of glaucoma, 2015 Apr .
How the study uses the data?
The study uses data from the FDA. It is based on acetazolamide and thiamine (vitamin b1) (the active ingredients of Acetazolamide and Thiamine, respectively), and Acetazolamide and Thiamine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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