Acetylcysteine and Reglan drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acetylcysteine (acetylcysteine) and Reglan (metoclopramide hydrochloride). Common drug interactions include asthma among females and gastrointestinal haemorrhage among males.
The phase IV clinical study analyzes what interactions people have when they take Acetylcysteine and Reglan. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Acetylcysteine?
Acetylcysteine has active ingredients of acetylcysteine. It is often used in cough. eHealthMe is studying from 11,563 Acetylcysteine users. Check the latest studies of Acetylcysteine.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
36 people who take Acetylcysteine and Reglan together, and have interactions are studied.

What are the common drug interactions of Acetylcysteine and Reglan, by gender? *:
female:
- Asthma
- Back pain
- Blood carbon dioxide decreased
- Blood magnesium decreased
- Blood potassium decreased
- Blood pressure increased
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Cardiac arrest
- Cardiac disorder
- Cardiac failure
male:
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Haematoma (collection of blood outside the blood vessels)
- Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
- Hepatic failure (liver failure)
- Liver disorder (liver diseases)
- Pulmonary hypertension (increase in blood pressure in the lung artery)
- Renal failure acute (rapid kidney dysfunction)
- Thrombocytopenia (decrease of platelets in blood)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
What are the common drug interactions of Acetylcysteine and Reglan, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Anaemia (lack of blood)
- Blood carbon dioxide decreased
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Cyanosis peripheral (blue tint in fingers or extremities, due to inadequate circulation)
- Drug toxicity
- Fungaemia (fungi circulate in the blood)
- Hypocalcaemia (levels of calcium in blood serum are abnormally low)
- Hypoxia (low oxygen in tissues)
- Methaemoglobinaemia (a disorder characterized by the presence of a higher than normal level of methemoglobin in blood)
- Multi-organ failure (multisystem organ failure)
20-29:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dystonia (abnormal muscle tone)
30-39:
- Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
- Dyspnoea (difficult or laboured respiration)
- Face oedema (swelling of face)
- Oxygen saturation decreased
- Pruritus (severe itching of the skin)
- Urticaria (rash of round, red welts on the skin that itch intensely)
40-49:
- Mucosal inflammation (infection of mucous membrane)
- Vomiting
- Asthma
- Disease recurrence
- Food intolerance (inability to have food)
- Gastrointestinal inflammation (inflammation of stomach and intestine)
- Hepatic enzyme increased
- Hepatitis viral
- Increased upper airway secretion
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
50-59:
- Fall
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Heart rate irregular
- Hyperhidrosis (abnormally increased sweating)
- Hypersomnia (excessive daytime sleepiness (eds))
- Hypervolaemia (abnormally increased volume of blood)
- Hypotension (abnormally low blood pressure)
- Incoherent (talking in a confused and unclear way)
- Infection
60+:
- Fall
- Anxiety
- Tibia fracture (fracture of lower leg bone)
- Upper limb fracture
- Diarrhoea
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Blood alkaline phosphatase increased
- Blood creatinine increased
- Blood magnesium decreased
- Blood potassium decreased
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.33%
- Pain: 3 people, 8.33%
- Meningitis Fungal (fungal inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges): 3 people, 8.33%
- Indigestion: 3 people, 8.33%
- Depression: 3 people, 8.33%
- Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 5.56%
- Stress And Anxiety: 2 people, 5.56%
- Oral Cancer (mouth cancer): 2 people, 5.56%
- Oedema (fluid collection in tissue): 2 people, 5.56%
- High Blood Cholesterol: 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Acetylcysteine and Reglan?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Acetylcysteine (11,563 reports)
- Reglan (29,455 reports)
Browse all drug interactions of Acetylcysteine and Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acetylcysteine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acetylcysteine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetylcysteine and metoclopramide hydrochloride (the active ingredients of Acetylcysteine and Reglan, respectively), and Acetylcysteine and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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