Aciphex and Isosorbide dinitrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Aciphex (rabeprazole sodium) and Isosorbide dinitrate (isosorbide dinitrate). Common drug interactions include lethargy among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Aciphex and Isosorbide dinitrate. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Aciphex?

Aciphex has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 25,301 Aciphex users. Check the latest studies of Aciphex.

What is Isosorbide dinitrate?

Isosorbide dinitrate has active ingredients of isosorbide dinitrate. It is often used in angina. eHealthMe is studying from 13,180 Isosorbide dinitrate users. Check the latest studies of Isosorbide dinitrate.

On Jul, 26, 2026

32 people who take Aciphex and Isosorbide dinitrate together, and have interactions are studied.

Aciphex and Isosorbide dinitrate drug interactions.

What are the common drug interactions of Aciphex and Isosorbide Dinitrate, by gender? *:

female:

Lethargy (tiredness)
Multiple injuries
Pain
Wrist fracture
Cardiac failure congestive
Carotid bruit (sound heard over the carotid artery area during auscultation)
Chest pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Death
Decreased appetite

male:

Chronic kidney disease
Injury
Drug ineffective
Emotional disorder
Memory impairment
Mitral valve incompetence (inefficient heart valve)
Pneumonia
Abdominal adhesions (inflammation of abdomen)
Abdominal pain
Abdominal tenderness

What are the common drug interactions of Aciphex and Isosorbide Dinitrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Dizziness
Loss of consciousness

50-59:

Chronic kidney disease
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cold sweat
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diabetes mellitus inadequate control
Diabetic nephropathy (diabetic kidney disease)
Diarrhoea
Diastolic dysfunction
Dilatation ventricular
Dyspnoea (difficult or laboured respiration)

60+:

Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Chronic kidney disease
Lethargy (tiredness)
Multiple injuries
Dizziness
Drug ineffective
Gastritis (inflammation of stomach)
Pain
Pneumonia
Radius fracture

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 15.62%
High Blood Cholesterol: 4 people, 12.50%
Diabetes: 4 people, 12.50%
Multiple Myeloma (cancer of the plasma cells): 3 people, 9.38%
Cardiac Failure Congestive: 3 people, 9.38%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 9.38%
Type 2 Diabetes: 2 people, 6.25%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 6.25%
Pain: 2 people, 6.25%
Hypokalemia (low potassium): 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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