Acitretin and Digoxin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Acitretin (acitretin) and Digoxin (digoxin). Common drug interactions include systemic lupus erythematosus among females and bowel movement irregularity among males.
The phase IV clinical study analyzes what interactions people have when they take Acitretin and Digoxin. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.
What is Acitretin?
Acitretin has active ingredients of acitretin. eHealthMe is studying from 5,515 Acitretin users. Check the latest studies of Acitretin.
What is Digoxin?
Digoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 93,740 Digoxin users. Check the latest studies of Digoxin.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
30 people who take Acitretin and Digoxin together, and have interactions are studied.

What are the common drug interactions of Acitretin and Digoxin, by gender? *:
female:
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
- Cerebral haemorrhage (bleeding within the brain)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Erythema (redness of the skin)
- Erythrodermic psoriasis (generalized redness of the skin)
- Euphoric mood (excessively happy but may become angry or irritable)
- Eye infection
- Eyelid disorder
- Hypertension (high blood pressure)
- Intracranial pressure increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid)
male:
- Bowel movement irregularity
- Bradycardia (abnormally slow heart action)
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Injection site erythema (redness at injection site)
- Pneumonia
- Cardiac failure
- Decreased appetite
- Dysphagia (a condition in which swallowing is difficult or painful)
- Infection
- Respiratory distress (difficulty in breathing)
What are the common drug interactions of Acitretin and Digoxin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
40-49:
n/a
50-59:
- Death
- Staphylococcal infection (an infection with staphylococcus bacteria)
60+:
- Bowel movement irregularity
- Bradycardia (abnormally slow heart action)
- Injection site erythema (redness at injection site)
- Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
- Pneumonia
- Cardiac failure
- Cerebral haemorrhage (bleeding within the brain)
- Decreased appetite
- Dysphagia (a condition in which swallowing is difficult or painful)
- Respiratory distress (difficulty in breathing)
What are the existing conditions these people have? *
- Psoriasis (immune-mediated disease that affects the skin): 14 people, 46.67%
- Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 16.67%
- Cardiac Failure Chronic: 4 people, 13.33%
- Euphoric Mood (excessively happy but may become angry or irritable): 3 people, 10.00%
- Confusion: 3 people, 10.00%
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 3 people, 10.00%
- Erythrodermic Psoriasis (generalized redness of the skin): 3 people, 10.00%
- Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 3 people, 10.00%
- Multiple Myeloma (cancer of the plasma cells): 3 people, 10.00%
- Myocardial Ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased): 3 people, 10.00%
* Approximation only. Some reports may have incomplete information.
Do you take Acitretin and Digoxin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Acitretin and Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Acitretin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Digoxin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Acitretin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Digoxin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
- Guru SR, Suresh A, Padmanabhan S, Reddy A, "A Rare Case of Digoxin Associated Gingival Overgrowth", Journal of clinical and diagnostic research: JCDR, 2017 Jan .
- Lai SW, Lin CL, Liao KF, "Digoxin use may increase the relative risk of acute pancreatitis: a population-based case–control study in Taiwan", International journal of cardiology, 2015 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on acitretin and digoxin (the active ingredients of Acitretin and Digoxin, respectively), and Acitretin and Digoxin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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