Acth and Enbrel drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acth (corticotropin) and Enbrel (etanercept). Common drug interactions include visual impairment among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Acth and Enbrel. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Acth?

Acth has active ingredients of corticotropin. eHealthMe is studying from 5,402 Acth users. Check the latest studies of Acth.

What is Enbrel?

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. eHealthMe is studying from 664,678 Enbrel users. Check the latest studies of Enbrel.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

33 people who take Acth and Enbrel together, and have interactions are studied.

What are the common drug interactions of Acth and Enbrel, by gender? *:

female:

Visual impairment
Swelling
Headache (pain in head)
Abdominal distension
Blood glucose increased
Cystitis (inflammation of the wall of the bladder)
Diarrhoea
Drug intolerance (drug sensitivity)
Insomnia (sleeplessness)
Osteopenia (a condition where bone mineral density is lower than normal)

male:

Arthralgia (joint pain)
Joint stiffness
Injection site erythema (redness at injection site)
Injection site pain
Injection site reaction
Injection site swelling
Neoplasm malignant (cancer tumour)
Joint swelling
Drug effect decreased
Drug ineffective

What are the common drug interactions of Acth and Enbrel, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chills (felling of cold)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Headache (pain in head)
Heart rate increased
Muscular weakness (muscle weakness)
Pain
Palpitations (feelings or sensations that your heart is pounding or racing)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Suicidal ideation

40-49:

Malaise (a feeling of general discomfort or uneasiness)
Surgery
Injection site erythema (redness at injection site)
Injection site pain
Injection site reaction
Injection site swelling

50-59:

Arthralgia (joint pain)
Joint swelling
Drug effect decreased
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Back pain
Erythema (redness of the skin)
Infection
Injection site pain
Joint stiffness
Pain in extremity

60+:

Abdominal distension
Blood glucose increased
Rash
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Drug eruption (adverse drug reaction of the skin)
Drug ineffective
Nasopharyngitis (inflammation of the nasopharynx)
Urticaria (rash of round, red welts on the skin that itch intensely)
Cystitis (inflammation of the wall of the bladder)
Diarrhoea

What are the existing conditions these people have? *

Urinary Tract Infection: 6 people, 18.18%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 5 people, 15.15%
Ankylosing Spondylitis (type of arthritis affecting the spine): 4 people, 12.12%
Polymyositis (inflammatory muscle disease that causes weakness of the skeletal muscles): 3 people, 9.09%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 6.06%
Swelling: 2 people, 6.06%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 6.06%
Diarrhea: 2 people, 6.06%
Dermatomyositis (inflammation of the skin and underlying muscle tissue, typically occurring as an autoimmune condition or associated with internal cancer): 2 people, 6.06%
Abdominal Distension: 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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