Actifed and Gaviscon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actifed (pseudoephedrine hydrochloride; triprolidine hydrochloride) and Gaviscon (aluminum hydroxide; magnesium trisilicate). Common drug interactions include decreased interest among females and deformity among males.
The phase IV clinical study analyzes what interactions people have when they take Actifed and Gaviscon. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.
What is Actifed?
Actifed has active ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,091 Actifed users. Check the latest studies of Actifed.
What is Gaviscon?
Gaviscon has active ingredients of aluminum hydroxide; magnesium trisilicate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 12,355 Gaviscon users. Check the latest studies of Gaviscon.
20 people who take Actifed and Gaviscon together, and have interactions are studied.

What are the common drug interactions of Actifed and Gaviscon, by gender? *:
female:
- Decreased interest
- Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
- Deformity (disfigurement)
- Emotional distress
- General physical health deterioration (weak health status)
- Gingival erythema (redness of gums)
- Gingival swelling (gums swelling)
- Gingival ulceration (ulcer on gums)
- Hot flush (sudden feelings of heat)
- Hypertension (high blood pressure)
male:
- Deformity (disfigurement)
- Depression
- Haemothorax (collection of blood in the pleural space (the space between the lungs and the walls of the chest))
- Hypotension (abnormally low blood pressure)
- Injury
- Overdose
- Pain
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Suicide attempt
- Abscess jaw (tooth abscess or root abscess)
What are the common drug interactions of Actifed and Gaviscon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pulmonary arterial hypertension (high blood pressure in the arteries of lungs)
30-39:
n/a
40-49:
n/a
50-59:
n/a
60+:
- Angioedema (rapid swelling of the dermis)
- Anxiety
- Emotional distress
- General physical health deterioration (weak health status)
- Gingival erythema (redness of gums)
- Gingival swelling (gums swelling)
- Gingival ulceration (ulcer on gums)
- Hot flush (sudden feelings of heat)
- Hypertension (high blood pressure)
- Hypophagia (reduced food intake)
What are the existing conditions these people have? *
- Hot Flush (sudden feelings of heat): 15 people, 75.00%
- Breast Cancer: 15 people, 75.00%
- Pain: 3 people, 15.00%
- Neuralgia (pain in one or more nerves): 3 people, 15.00%
- Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults): 2 people, 10.00%
- Allergic Rhinitis: 2 people, 10.00%
- Osteoporosis (bones weak and more likely to break): 1 person, 5.00%
- Hepatitis C: 1 person, 5.00%
- Blood Iron Increased: 1 person, 5.00%
* Approximation only. Some reports may have incomplete information.
Do you take Actifed and Gaviscon?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actifed and Gaviscon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actifed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Gaviscon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actifed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Gaviscon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on pseudoephedrine hydrochloride; triprolidine hydrochloride and aluminum hydroxide; magnesium trisilicate (the active ingredients of Actifed and Gaviscon, respectively), and Actifed and Gaviscon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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