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Actifed and Lialda drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actifed (pseudoephedrine hydrochloride; triprolidine hydrochloride) and Lialda (mesalamine). Common drug interactions include anaphylactic reaction among females.

The phase IV clinical study analyzes what interactions people have when they take Actifed and Lialda. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Actifed?

Actifed has active ingredients of pseudoephedrine hydrochloride; triprolidine hydrochloride. It is often used in allergies. eHealthMe is studying from 1,091 Actifed users. Check the latest studies of Actifed.

What is Lialda?

Lialda has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 10,199 Lialda users. Check the latest studies of Lialda.

On Jul, 28, 2026

33 people who take Actifed and Lialda together, and have interactions are studied.

Actifed and Lialda drug interactions.

What are the common drug interactions of Actifed and Lialda, by gender? *:

female:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Drug hypersensitivity
  3. Constipation
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Diarrhoea
  6. Dizziness
  7. Dysphagia (a condition in which swallowing is difficult or painful)
  8. Dysphoria (generalized dissatisfaction with life)
  9. Ear pain
  10. Fatigue (feeling of tiredness)

male:

n/a

What are the common drug interactions of Actifed and Lialda, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  3. Chills (felling of cold)
  4. Constipation
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Diarrhoea
  7. Dizziness
  8. Dysphagia (a condition in which swallowing is difficult or painful)
  9. Dysphoria (generalized dissatisfaction with life)
  10. Ear pain

What are the existing conditions these people have? *

  1. Dizziness: 29 people, 87.88%
  2. Pain: 11 people, 33.33%

* Approximation only. Some reports may have incomplete information.

Do you take Actifed and Lialda?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Actifed and Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actifed:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lialda:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actifed and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lialda and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on pseudoephedrine hydrochloride; triprolidine hydrochloride and mesalamine (the active ingredients of Actifed and Lialda, respectively), and Actifed and Lialda (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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