Actigall and Amaryl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actigall (ursodiol) and Amaryl (glimepiride). Common drug interactions include blood bilirubin increased among females and anastomotic stenosis among males.

The phase IV clinical study analyzes what interactions people have when they take Actigall and Amaryl. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

What is Amaryl?

Amaryl has active ingredients of glimepiride. It is often used in diabetes. eHealthMe is studying from 32,259 Amaryl users. Check the latest studies of Amaryl.

On Jul, 12, 2026

17 people who take Actigall and Amaryl together, and have interactions are studied.

What are the common drug interactions of Actigall and Amaryl, by gender? *:

female:

Blood bilirubin increased
Erythema (redness of the skin)
Fall
Foot ulcer
Hepatitis a antibody positive
Leg ulcer (exc varicose) (leg ulcer without varicose vein)
Markedly reduced food intake
Pain in limb
Pyrexia (fever)
Septicaemia escherichial (bacterial blood infection)

male:

Anastomotic stenosis
Cholangitis (infection of the bile duct)
Erythema (redness of the skin)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Gait disturbance
General physical health deterioration (weak health status)
Hepatic artery occlusion (the blockage in hepatic artery)
Hyperkeratosis (thickening of the outer layer of the skin)
Hypoaesthesia (reduced sense of touch or sensation)
Joint contracture (a permanent shortening of a muscle or joint)

What are the common drug interactions of Actigall and Amaryl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Post procedural complication
Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary mass
Pyrexia (fever)
Secondary adrenocortical insufficiency (inadequate secretion of acth by the pituitary gland)
Sepsis (a severe blood infection that can lead to organ failure and death)
Septicaemia escherichial (bacterial blood infection)
Skin discolouration (change of skin colour)
Thrombocytopenia (decrease of platelets in blood)
Urinary tract infection enterococcal

60+:

Abscess jaw (tooth abscess or root abscess)
Arteriosclerosis (thickening and hardening of arteries)
Excessive granulation tissue (excessive collagen-rich tissue which forms at the site of an injury)
Eye pruritus (eye itching)
Fatigue (feeling of tiredness)
Fistula (an abnormal connection or passageway between two)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypogonadism male (male testes produce little or no sex hormone)
Impaired healing

What are the existing conditions these people have? *

Liver Transplant Rejection (failure of liver transplant): 4 people, 23.53%
Nuclear Magnetic Resonance Imaging Brain: 3 people, 17.65%
Pyogenic Liver Abscess (liver abscess caused by bacteria): 2 people, 11.76%
Urinary Tract Infection: 1 person, 5.88%
High Blood Pressure: 1 person, 5.88%
Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 1 person, 5.88%
Depression: 1 person, 5.88%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 5.88%
Constipation: 1 person, 5.88%
Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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