Actigall and Micafungin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actigall (ursodiol) and Micafungin (micafungin sodium). Common drug interactions include venoocclusive liver disease among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Actigall and Micafungin. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

What is Micafungin?

Micafungin has active ingredients of micafungin sodium. eHealthMe is studying from 6,562 Micafungin users. Check the latest studies of Micafungin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

47 people who take Actigall and Micafungin together, and have interactions are studied.

Actigall and Micafungin drug interactions.

What are the common drug interactions of Actigall and Micafungin, by gender? *:

female:

Venoocclusive liver disease (small veins in the liver are obstructed)
Abdominal distension
Hepatic failure (liver failure)
Immunosuppression
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Agitation (state of anxiety or nervous excitement)
Anaemia (lack of blood)
Anxiety
Bacteraemia (presence of bacteria in the blood)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

male:

Hypertension (high blood pressure)
Acidosis (build-up of carbon dioxide in the blood)
Constipation
Cough
Cystic fibrosis (disease of the secretary glands)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

What are the common drug interactions of Actigall and Micafungin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal distension
Acute graft versus host disease in intestine (acute complication in intestine following an allogeneic tissue/blood transplant)
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Adenovirus infection
Ascites (accumulation of fluid in the abdominal cavity)
Bacteraemia (presence of bacteria in the blood)
Bk virus infection
Blood pressure systolic decreased
Brain death

10-19:

B-cell type acute leukaemia (cancer of the white blood cells)
Disease progression
Transaminases increased
Fluid overload (too much fluid in the blood)
Gastritis (inflammation of stomach)
Herpes simplex (herpes simplex is a common viral infection)
Neurotoxicity (when the exposure to natural or artificial toxic substances, which are called neurotoxins, alters the normal activity of the nervous system)
Pericardial haemorrhage (bleeding into the heart)
Pneumonia
Renal impairment (severely reduced kidney function)

20-29:

Aspartate aminotransferase increased
Blood bilirubin increased
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Alanine aminotransferase increased
Cholecystitis (infection of gallbladder)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Gamma-glutamyltransferase increased
Haemorrhage intracranial (bleeding within the skull)
Hepatitis (inflammation of the liver)
Hepatomegaly (abnormal enlargement of the liver)

30-39:

Acidosis (build-up of carbon dioxide in the blood)
Acute respiratory distress syndrome
Anaemia (lack of blood)
Asthenia (weakness)
Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
Blood creatinine increased
Blood urea increased
Bronchial haemorrhage (bleeding in bronchia)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Constipation

40-49:

Drug resistance (reduction in effectiveness of a drug)
Headache (pain in head)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

50-59:

Respiratory failure (inadequate gas exchange by the respiratory system)
Bradycardia (abnormally slow heart action)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hepatic artery occlusion (the blockage in hepatic artery)
Hypertension (high blood pressure)
Oxygen saturation decreased
Abdominal pain
Acute respiratory distress syndrome
Aortic dilatation
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

60+:

Enterococcal infection
Diarrhoea
Acute myeloid leukaemia recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent)
Chills (felling of cold)
Haemosiderosis (general increase in tissue iron stores without associated tissue damage)
Hyperglycaemia (high blood sugar)
Hypermagnesaemia (an electrolyte disturbance in which there is an abnormally elevated level of magnesium in the blood)
Oral candidiasis (fungal infection of mouth)
Pulmonary oedema (fluid accumulation in the lungs)
Venoocclusive liver disease (small veins in the liver are obstructed)

What are the existing conditions these people have? *

Pain: 17 people, 36.17%
High Blood Pressure: 14 people, 29.79%
Nausea (feeling of having an urge to vomit): 14 people, 29.79%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 23.40%
Fungal Infection: 11 people, 23.40%
Sedation: 10 people, 21.28%
Agitation (state of anxiety or nervous excitement): 10 people, 21.28%
Cough: 10 people, 21.28%
Wheezing (a high-pitched whistling sound made while you breath): 9 people, 19.15%
Asthma: 9 people, 19.15%

* Approximation only. Some reports may have incomplete information.

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