Actimmune and Vitamin d drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actimmune (interferon gamma-1b) and Vitamin d (ergocalciferol). Common drug interactions include cold sweat among females and abscess neck among males.
The phase IV clinical study analyzes what interactions people have when they take Actimmune and Vitamin d. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Actimmune?
Actimmune has active ingredients of interferon gamma-1b. eHealthMe is studying from 1,734 Actimmune users. Check the latest studies of Actimmune.
What is Vitamin d?
Vitamin d has active ingredients of ergocalciferol. It is often used in low vitamin d. eHealthMe is studying from 294,094 Vitamin d users. Check the latest studies of Vitamin d.
12 people who take Actimmune and Vitamin d together, and have interactions are studied.

What are the common drug interactions of Actimmune and Vitamin D, by gender? *:
female:
- Cold sweat
- Insomnia (sleeplessness)
- Chills (felling of cold)
- Lung infection
- Pain
- Pyrexia (fever)
- Respiratory failure (inadequate gas exchange by the respiratory system)
male:
- Abscess neck (neck abscesses)
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Nocardiosis (an infectious disease affecting either the lungs or whole body)
- Pain
- Pyrexia (fever)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- White blood cell count decreased
- Epiglottitis (inflammation of the epiglottis)
- Fatigue (feeling of tiredness)
- Fungal infection
What are the common drug interactions of Actimmune and Vitamin D, by age (0-1 to 60+)? *:
0-1:
- Lung infection
- Respiratory failure (inadequate gas exchange by the respiratory system)
2-9:
- Abscess neck (neck abscesses)
- Epiglottitis (inflammation of the epiglottis)
- Lymphadenitis (inflammation or enlargement of a lymph node)
- Nocardiosis (an infectious disease affecting either the lungs or whole body)
- Somnolence (a state of near-sleep, a strong desire for sleep)
10-19:
- Infection
- Injection site pain
- Local swelling (swelling at the site of some application of substance or injury)
20-29:
- Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)
- Fungal infection
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Pyrexia (fever)
- White blood cell count decreased
30-39:
n/a
40-49:
n/a
50-59:
- Chills (felling of cold)
- Fatigue (feeling of tiredness)
- Pain
60+:
- Cold sweat
- Insomnia (sleeplessness)
What are the existing conditions these people have? *
- Chronic Granulomatous Disease (immune system cells are unable to kill some types of bacteria and fungi): 5 people, 41.67%
- White Blood Cell Count Abnormal: 2 people, 16.67%
- Mycosis Fungoides (lymphocytes (a type of white blood cell) become malignant (cancerous) and affect the skin): 1 person, 8.33%
- Friedreich's Ataxia (damage to the nervous system): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Actimmune and Vitamin d?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actimmune and Vitamin d:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actimmune:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Vitamin d:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actimmune and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Vitamin d and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on interferon gamma-1b and ergocalciferol (the active ingredients of Actimmune and Vitamin d, respectively), and Actimmune and Vitamin d (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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