Actiq and Metronidazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actiq (fentanyl citrate) and Metronidazole (metronidazole). Common drug interactions include headache among females and blood pressure systolic increased among males.

The phase IV clinical study analyzes what interactions people have when they take Actiq and Metronidazole. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

What is Metronidazole?

Metronidazole has active ingredients of metronidazole. It is often used in vaginitis bacterial. eHealthMe is studying from 59,578 Metronidazole users. Check the latest studies of Metronidazole.

On Jul, 04, 2026

16 people who take Actiq and Metronidazole together, and have interactions are studied.

Actiq and Metronidazole drug interactions.

What are the common drug interactions of Actiq and Metronidazole, by gender? *:

female:

Headache (pain in head)
Muscular weakness (muscle weakness)
Abscess oral (abscess in the mouth)
Anaemia (lack of blood)
Arteriosclerosis (thickening and hardening of arteries)
Bladder prolapse (bulging of one or more of the pelvic organs into the vagina)
Bone disorder
Bone fistula
Cardiac failure congestive
Carotid artery stenosis (narrowing of carotid artery)

male:

Blood pressure systolic increased
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Small intestinal obstruction (blockage in small intestine)
Staphylococcal infection (an infection with staphylococcus bacteria)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Culture positive
Dehydration (dryness resulting from the removal of water)
Electrolyte imbalance
Erythema (redness of the skin)
Escherichia infection (bacterial infection by escherichia coli)

What are the common drug interactions of Actiq and Metronidazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Erythema (redness of the skin)
Labile blood pressure (wildly fluctuating blood pressure)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

20-29:

n/a

30-39:

Blood pressure systolic increased
Clostridium colitis (inflammation of colon by clostridium difficile bacteria infection)
Culture positive
Dehydration (dryness resulting from the removal of water)
Electrolyte imbalance
Escherichia infection (bacterial infection by escherichia coli)
Pathogen resistance
Sepsis (a severe blood infection that can lead to organ failure and death)
Small intestinal obstruction (blockage in small intestine)
Staphylococcal infection (an infection with staphylococcus bacteria)

40-49:

n/a

50-59:

n/a

60+:

Abscess oral (abscess in the mouth)
Anaemia (lack of blood)
Chronic inflammatory demyelinating polyradiculoneuropathy (long lasting infection of nerves outside brain and spinal cord)
Colostomy
Contusion (a type of hematoma of tissue in which capillaries)
Deafness
Depression
Device failure
Diarrhoea
Dysaesthesia (abnormal sensation)

What are the existing conditions these people have? *

Colorectal Cancer Metastatic (cancer of colon and rectal spreads to other parts): 2 people, 12.50%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 1 person, 6.25%
Psychotic Disorder: 1 person, 6.25%
Metastases To Bone (cancer spreads to bone): 1 person, 6.25%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.25%
Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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