Actiq and Singulair drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actiq (fentanyl citrate) and Singulair (montelukast sodium). Common drug interactions include vascular rupture among females and pneumonia among males.

The phase IV clinical study analyzes what interactions people have when they take Actiq and Singulair. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Actiq?

Actiq has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 27,583 Actiq users. Check the latest studies of Actiq.

What is Singulair?

Singulair has active ingredients of montelukast sodium. It is often used in asthma. eHealthMe is studying from 129,752 Singulair users. Check the latest studies of Singulair.

On Jul, 10, 2026

43 people who take Actiq and Singulair together, and have interactions are studied.

What are the common drug interactions of Actiq and Singulair, by gender? *:

female:

Vascular rupture
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Constipation
Cystitis (inflammation of the wall of the bladder)
Dehydration (dryness resulting from the removal of water)
Dry mouth
Dysarthria (speech disorder)
Dyspnoea (difficult or laboured respiration)
Gingival infection (gum infection)

male:

Pneumonia
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Bone disorder
Breath odour
Cardiac arrest
Cataract (clouding of the lens inside the eye)
Cerebral atrophy (decrement in size of brain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Decreased activity
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)

What are the common drug interactions of Actiq and Singulair, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Arthralgia (joint pain)
Bone pain
Discomfort
Influenza like illness
Infusion site pain
Myalgia (muscle pain)
Nephrolithiasis (calculi in the kidneys)
Post procedural complication
Post procedural swelling
Pyrexia (fever)

40-49:

Muscle spasms (muscle contraction)
Palpitations (feelings or sensations that your heart is pounding or racing)

50-59:

Osteomyelitis (infection of bone)
Pain in extremity
Pain in jaw
Pleural effusion (water on the lungs)
Purulence (containing pus)
Renal failure (kidney dysfunction)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Subcutaneous abscess
Swelling
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot)

60+:

Stomatitis (inflammation of mucous membrane of mouth)
Asthenia (weakness)
Femoral hernia, obstructive (when a part of the intestine becomes intertwined with the hernia, causing an intestinal obstruction)
Hypoaesthesia (reduced sense of touch or sensation)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pneumonia
Pyrexia (fever)
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)
Alopecia (absence of hair from areas of the body)

What are the existing conditions these people have? *

Metastases To Bone (cancer spreads to bone): 9 people, 20.93%
High Blood Pressure: 7 people, 16.28%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 13.95%
Depression: 6 people, 13.95%
Nausea (feeling of having an urge to vomit): 5 people, 11.63%
High Blood Cholesterol: 5 people, 11.63%
Fibromyalgia (a long-term condition which causes pain all over the body): 5 people, 11.63%
Seasonal Allergy (allergic condition due to certain season): 4 people, 9.30%
Osteoporosis (bones weak and more likely to break): 4 people, 9.30%
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it): 4 people, 9.30%

* Approximation only. Some reports may have incomplete information.

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