Activase and Daptomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Activase (alteplase) and Daptomycin (daptomycin). Common drug interactions include bone marrow failure among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Activase and Daptomycin. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Activase?

Activase has active ingredients of alteplase. eHealthMe is studying from 7,526 Activase users. Check the latest studies of Activase.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

On Jul, 25, 2026

12 people who take Activase and Daptomycin together, and have interactions are studied.

Activase and Daptomycin drug interactions.

What are the common drug interactions of Activase and Daptomycin, by gender? *:

female:

Bone marrow failure
Cardiac failure congestive
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fungal skin infection
Pneumonia fungal
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Arthralgia (joint pain)
Back pain
Constipation
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

male:

Ascites (accumulation of fluid in the abdominal cavity)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Multi-organ failure (multisystem organ failure)
Pleural effusion (water on the lungs)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Proctalgia (pain in the rectum)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Respiratory distress (difficulty in breathing)
Venoocclusive liver disease (small veins in the liver are obstructed)

What are the common drug interactions of Activase and Daptomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bone marrow failure
Cardiac failure congestive
Enterococcal bacteraemia (presence of bacteria lactic acid in the blood)
Fungal skin infection
Pneumonia fungal

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Intestinal ischaemia (decreased supply of oxygenated blood to the intestines)
Lymphoma (cancer that begins in immune system cells)

50-59:

Drug hypersensitivity
Leukocytosis (increased white blood cells)
Pyrexia (fever)

60+:

Ascites (accumulation of fluid in the abdominal cavity)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Multi-organ failure (multisystem organ failure)
Pleural effusion (water on the lungs)
Pneumonia bacterial (pneumonia associated with bacterial infection)
Proctalgia (pain in the rectum)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Respiratory distress (difficulty in breathing)
Venoocclusive liver disease (small veins in the liver are obstructed)

What are the existing conditions these people have? *

Infection: 3 people, 25.00%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 3 people, 25.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 16.67%
Thrombolysis (resolving the blood clot): 1 person, 8.33%
Migraine (headache): 1 person, 8.33%
Lymphoma (cancer that begins in immune system cells): 1 person, 8.33%
Haematopoietic Stem Cell Mobilisation: 1 person, 8.33%
Endocarditis (inflammation in heart muscle): 1 person, 8.33%
Device Occlusion: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

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