Activella and Ergocalciferol drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Activella (estradiol; norethindrone acetate) and Ergocalciferol (ergocalciferol). Common drug interactions include bone density decreased among females.
The phase IV clinical study analyzes what interactions people have when they take Activella and Ergocalciferol. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Activella?
Activella has active ingredients of estradiol; norethindrone acetate. It is often used in menopause. eHealthMe is studying from 1,971 Activella users. Check the latest studies of Activella.
What is Ergocalciferol?
Ergocalciferol has active ingredients of ergocalciferol. It is often used in rickets. eHealthMe is studying from 32,652 Ergocalciferol users. Check the latest studies of Ergocalciferol.
19 people who take Activella and Ergocalciferol together, and have interactions are studied.

What are the common drug interactions of Activella and Ergocalciferol, by gender? *:
female:
- Bone density decreased
- Ankle fracture
- Dyspnoea (difficult or laboured respiration)
- Infection
- Live birth
- Maternal exposure during pregnancy (use of substance during pregnancy)
- Alopecia (absence of hair from areas of the body)
- Road traffic accident
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
male:
n/a
What are the common drug interactions of Activella and Ergocalciferol, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cholecystitis chronic (long lasting infection of gallbladder)
- Live birth
- Maternal exposure during pregnancy (use of substance during pregnancy)
30-39:
- Aspartate aminotransferase increased
- Asthma
- Dyspnoea (difficult or laboured respiration)
- Bone density decreased
- Alanine aminotransferase increased
- Ankle fracture
40-49:
- Bone density decreased
- Alopecia (absence of hair from areas of the body)
50-59:
- Bone density decreased
- Ankle fracture
- Road traffic accident
60+:
- Breast cancer
- Chronic kidney disease
What are the existing conditions these people have? *
- Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 12 people, 63.16%
- Anaemia (lack of blood): 5 people, 26.32%
- High Blood Pressure: 4 people, 21.05%
- Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain): 3 people, 15.79%
- Seasonal Allergy (allergic condition due to certain season): 3 people, 15.79%
- Vitamin D Decreased: 3 people, 15.79%
- Migraine (headache): 3 people, 15.79%
- Abdominal Pain Lower: 2 people, 10.53%
- Type 2 Diabetes: 2 people, 10.53%
- Stress And Anxiety: 2 people, 10.53%
* Approximation only. Some reports may have incomplete information.
Do you take Activella and Ergocalciferol?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Activella (1,971 reports)
- Ergocalciferol (32,652 reports)
Browse all drug interactions of Activella and Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Activella:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ergocalciferol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Activella and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ergocalciferol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
- Kapoor S, "Influence of Vitamin D Consumption and Levels on the Development of Psychiatric Disorders", Lee, Y. J., & Park, K. (2018). Secondary Raynaud’s Phenomenon and Skin Necrosis of Toes in the Paraplegic Patient with Hypertension.?Drug safety-case reports,?5(1), 7., 2014 Aug .
How the study uses the data?
The study uses data from the FDA. It is based on estradiol; norethindrone acetate and ergocalciferol (the active ingredients of Activella and Ergocalciferol, respectively), and Activella and Ergocalciferol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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