Actonel and Buspirone hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Buspirone hcl (buspirone hydrochloride). Common drug interactions include extrapyramidal disorder among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Buspirone hcl. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Buspirone hcl?

Buspirone hcl has active ingredients of buspirone hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 9,821 Buspirone hcl users. Check the latest studies of Buspirone hcl.

On Jul, 09, 2026

24 people who take Actonel and Buspirone hcl together, and have interactions are studied.

Actonel and Buspirone hcl drug interactions.

What are the common drug interactions of Actonel and Buspirone Hcl, by gender? *:

female:

Extrapyramidal disorder (involuntary muscle spasms in the face and neck)
Facial pain
Feeling cold
Feeling jittery
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Haematuria (presence of blood in urine)
Heart rate irregular
Helicobacter test positive
Hepatic cyst

male:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bacterial prostatitis (bacterial infection of the prostate gland)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure (kidney dysfunction)
Renal injury (kidney injury)
Sepsis (a severe blood infection that can lead to organ failure and death)
Abdominal pain
Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Congestive cardiomyopathy (weakening of heart muscle)

What are the common drug interactions of Actonel and Buspirone Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Hair colour changes
Hair disorder
Post-traumatic stress disorder
Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)

50-59:

Drug ineffective
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Bacterial prostatitis (bacterial infection of the prostate gland)
Blood hiv rna increased
Bone density decreased
Complex partial seizures (epileptic seizure)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Emotional distress
Fracture
Genotype drug resistance test positive

60+:

Bone disorder
Abdominal discomfort
Procedural pain
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Bacteraemia (presence of bacteria in the blood)
Cellulitis (infection under the skin)
Joint dislocation (a joint position is changed from normal position)
Osteomyelitis chronic (long lasting infection of bone marrow)
Osteonecrosis (death of bone)
Wound infection

What are the existing conditions these people have? *

Ovarian Cancer (cancer of ovary): 4 people, 16.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 12.50%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 12.50%
High Blood Pressure: 3 people, 12.50%
High Blood Cholesterol: 3 people, 12.50%
Depression: 3 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 8.33%
Multiple Allergies (allergy to multiple agents): 2 people, 8.33%
Hiv Infection: 2 people, 8.33%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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