Actonel and Docetaxel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actonel (risedronate sodium) and Docetaxel (docetaxel). Common drug interactions include abdominal rigidity among females and febrile neutropenia among males.
The phase IV clinical study analyzes what interactions people have when they take Actonel and Docetaxel. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.
What is Actonel?
Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.
What is Docetaxel?
Docetaxel has active ingredients of docetaxel. eHealthMe is studying from 79,875 Docetaxel users. Check the latest studies of Docetaxel.
38 people who take Actonel and Docetaxel together, and have interactions are studied.

What are the common drug interactions of Actonel and Docetaxel, by gender? *:
female:
- Abdominal rigidity
- Abdominal symptom
- Anaphylactic reaction (serious allergic reaction)
- Anger
- Angiofibroma (small, reddish brown or even flesh-coloured, smooth, shiny, 0.1- to 0.3 cm papules present over the sides of the nose and the medial portions of the cheeks)
- Areflexia (absence of a reflex)
- Arthralgia (joint pain)
- Arthropathy
- Ascites (accumulation of fluid in the abdominal cavity)
- Asthma
male:
- Febrile neutropenia (fever with reduced white blood cells)
- Pneumonia
- Renal failure (kidney dysfunction)
- Chondropathy (disease of the cartilage)
- Oesophageal spasm (contraction of oesophagus)
- Aspartate aminotransferase increased
- Blood alkaline phosphatase increased
- Blood calcium decreased
- Blood creatinine decreased
- Blood glucose increased
What are the common drug interactions of Actonel and Docetaxel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Breast cancer female
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
40-49:
- Alopecia (absence of hair from areas of the body)
- Hair colour changes
- Hair disorder
- Post-traumatic stress disorder
- Anxiety
- Major depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings)
50-59:
- Asthma
- Back pain
- Balance disorder
- Bone disorder
- Bone pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cellulitis (infection under the skin)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
60+:
- Febrile neutropenia (fever with reduced white blood cells)
- Hair colour changes
- Vomiting
- Acute hepatic failure
- Dehydration (dryness resulting from the removal of water)
- Depression
- Duodenal stenosis (block of the first part of the small intestine)
- Haematocrit decreased
- Haemoglobin decreased
- Hypotension (abnormally low blood pressure)
What are the existing conditions these people have? *
- Prostate Cancer: 14 people, 36.84%
- Breast Cancer: 9 people, 23.68%
- Ovarian Cancer (cancer of ovary): 4 people, 10.53%
- Breast Cancer Female: 4 people, 10.53%
- High Blood Pressure: 3 people, 7.89%
- Gastritis (inflammation of stomach): 3 people, 7.89%
- Diabetes: 3 people, 7.89%
- Lupus Nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue): 2 people, 5.26%
- Insomnia (sleeplessness): 2 people, 5.26%
- Indigestion: 2 people, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Actonel and Docetaxel?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actonel and Docetaxel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actonel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Docetaxel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actonel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Docetaxel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Byun JS, Kang SH, Lee MJ, Kim SY, Choi HG, Lee HR, "A Case of Scleroderma-like Cutaneous Lesions Induced by Docetaxel in a Patient with Breast Cancer", Journal of Rheumatic Diseases, 2013 Oct .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
- Hirschmann S, Gibel A, Tsvelikhovsky I, Lisker A, "Late-Onset Psychosis and Risedronate Treatment for Osteoporosis: A Case Report", Clinical schizophrenia & related psychoses, 2013 May .
- Byun JS, Kang SH, Lee MJ, Kim SY, Choi HG, Lee HR, "A Case of Scleroderma-like Cutaneous Lesions Induced by Docetaxel in a Patient with Breast Cancer", Journal of Rheumatic Diseases, 2013 Oct .
- Ko KD, Cho BL, "Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis", Journal of the Korean Geriatrics Society, 2012 Dec .
How the study uses the data?
The study uses data from the FDA. It is based on risedronate sodium and docetaxel (the active ingredients of Actonel and Docetaxel, respectively), and Actonel and Docetaxel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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