Actonel and Monopril drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Monopril (fosinopril sodium). Common drug interactions include fall among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Monopril. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Monopril?

Monopril has active ingredients of fosinopril sodium. It is often used in high blood pressure. eHealthMe is studying from 5,910 Monopril users. Check the latest studies of Monopril.



On Jul, 07, 2026

38 people who take Actonel and Monopril together, and have interactions are studied.

Actonel and Monopril drug interactions.

What are the common drug interactions of Actonel and Monopril, by gender? *:

female:

  1. Fall
  2. Cerebral infarction (less blood supply to brain resulting tissue damage)
  3. Chills (felling of cold)
  4. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  5. Abscess oral (abscess in the mouth)
  6. Ear pain
  7. Facial pain
  8. Fluid intake reduced
  9. Gingival swelling (gums swelling)
  10. Hypophagia (reduced food intake)

male:

  1. Arthralgia (joint pain)
  2. Anaemia (lack of blood)
  3. Drug effect decreased
  4. Dysphonia (speech disorder attributable to a disorder of phonation)
  5. Haemoglobin decreased
  6. Malignant melanoma (skin cancer rises from melancytes)

What are the common drug interactions of Actonel and Monopril, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Arthralgia (joint pain)
  2. Anaemia (lack of blood)
  3. Haemoglobin decreased

40-49:

  1. Pathological fracture (broken bone caused by disease)
  2. Abscess jaw (tooth abscess or root abscess)
  3. Cellulitis (infection under the skin)
  4. Fistula (an abnormal connection or passageway between two)
  5. Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
  6. Mouth ulceration (mouth ulcers)
  7. Osteomyelitis (infection of bone)
  8. Osteonecrosis (death of bone)
  9. Pain in jaw
  10. Post procedural infection

50-59:

  1. Body temperature increased
  2. Cardiac disorder
  3. Carotid artery occlusion (artery blockage)
  4. Carotid artery stenosis (narrowing of carotid artery)
  5. Carotid bruit (sound heard over the carotid artery area during auscultation)
  6. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  7. Chest pain
  8. Contusion (a type of hematoma of tissue in which capillaries)
  9. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  10. Depression

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Infusion related reaction
  3. Vomiting
  4. Adverse event
  5. Blood creatine phosphokinase increased
  6. Bone disorder
  7. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  8. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  9. Chest pain
  10. Limb injury

What are the existing conditions these people have? *

  1. Rheumatoid Vasculitis (inflammation of veins with painful joints and morning stiffness): 4 people, 10.53%
  2. Polyneuropathy (neurological disorder that occurs when many peripheral nerves throughout the body malfunction simultaneously): 4 people, 10.53%
  3. Hip Fracture: 3 people, 7.89%
  4. High Blood Cholesterol: 3 people, 7.89%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Actonel and Monopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actonel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Monopril:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actonel and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Monopril and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risedronate sodium and fosinopril sodium (the active ingredients of Actonel and Monopril, respectively), and Actonel and Monopril (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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