Actonel and Perphenazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Perphenazine (perphenazine). Common drug interactions include dry eye among females.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Perphenazine. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Perphenazine?

Perphenazine has active ingredients of perphenazine. It is often used in bipolar i disorder. eHealthMe is studying from 2,712 Perphenazine users. Check the latest studies of Perphenazine.

On Jul, 12, 2026

73 people who take Actonel and Perphenazine together, and have interactions are studied.

Actonel and Perphenazine drug interactions.

What are the common drug interactions of Actonel and Perphenazine, by gender? *:

female:

Dry eye (lack of adequate tears)
Fatigue (feeling of tiredness)
Infection
Nausea (feeling of having an urge to vomit)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Presbyacusis (age-related hearing loss)
Renal impairment (severely reduced kidney function)
Skin lesion
Sleep disorder
Blood magnesium increased

male:

n/a

What are the common drug interactions of Actonel and Perphenazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Sinusitis (inflammation of sinus)
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
Sleep disorder
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Tendon disorder (disease of tendon)
Tooth disorder (tooth disease)
Type 2 diabetes mellitus
Anaemia (lack of blood)
Arthralgia (joint pain)
Back pain

40-49:

n/a

50-59:

n/a

60+:

Cyst (a closed sac)
Deafness neurosensory
Nausea (feeling of having an urge to vomit)
Blood creatinine increased
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Presbyacusis (age-related hearing loss)
Renal impairment (severely reduced kidney function)
Skin lesion
Blood magnesium increased
Blood potassium increased

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 71 people, 97.26%
Pain: 65 people, 89.04%
Sleep Disorder: 59 people, 80.82%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 57 people, 78.08%
Dry Eyes (lack of adequate tears): 22 people, 30.14%
Adenomatous Polyposis Coli ((fap) is an inherited condition in which numerous polyps form mainly in the epithelium of the large intestine): 20 people, 27.40%

* Approximation only. Some reports may have incomplete information.

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