Actonel and Precose drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Precose (acarbose). Common drug interactions include femur fracture among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Precose. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Precose?

Precose has active ingredients of acarbose. eHealthMe is studying from 1,189 Precose users. Check the latest studies of Precose.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

13 people who take Actonel and Precose together, and have interactions are studied.

What are the common drug interactions of Actonel and Precose, by gender? *:

female:

Femur fracture
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)
Stress fracture (fracture of a bone caused by repeated (rather than sudden) mechanical stress)
Arthralgia (joint pain)
Bone disorder
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Mobility decreased (ability to move is reduced)
Osteoporotic fracture (fracture due to weak bone)

male:

Arthralgia (joint pain)
Femur fracture
Bone disorder
Dysstasia (difficulty in standing)
Fracture delayed union (delayed cure of broken bone)
Fracture displacement
Fracture nonunion (permanent failure of healing following a broken bone)
Groin pain
Haematoma (collection of blood outside the blood vessels)
Low turnover osteopathy (slow removal of old bone and its replacement by new bone)

What are the common drug interactions of Actonel and Precose, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal distension
Arthralgia (joint pain)
Back pain
Bone disorder
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dysstasia (difficulty in standing)
Fatigue (feeling of tiredness)
Femur fracture
Fracture delayed union (delayed cure of broken bone)

40-49:

Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Oedema peripheral (superficial swelling)
Pain in extremity

50-59:

Groin pain
Mobility decreased (ability to move is reduced)
Osteoporotic fracture (fracture due to weak bone)
Pain
Pathological fracture (broken bone caused by disease)
Fall
Mass
Staphylococcal infection (an infection with staphylococcus bacteria)
Hip deformity
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)

60+:

Abdominal pain upper
Pancreatitis (inflammation of pancreas)
Renal cyst (kidney cyst)

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 3 people, 23.08%
Pain: 2 people, 15.38%
Intracranial Pressure Increased (high pressure inside the skull and thus in the brain tissue and cerebrospinal fluid): 2 people, 15.38%
Indigestion: 2 people, 15.38%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 15.38%
Hypersensitivity: 2 people, 15.38%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 2 people, 15.38%
Endocrine Disorder (endocrine diseases are disorders of the endocrine system): 2 people, 15.38%
Type 2 Diabetes: 1 person, 7.69%
Csf Test Abnormal: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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