Actonel and Trilafon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actonel (risedronate sodium) and Trilafon (perphenazine). Common drug interactions include hyperlipidaemia among females.

The phase IV clinical study analyzes what interactions people have when they take Actonel and Trilafon. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Actonel?

Actonel has active ingredients of risedronate sodium. It is often used in osteoporosis. eHealthMe is studying from 29,369 Actonel users. Check the latest studies of Actonel.

What is Trilafon?

Trilafon has active ingredients of perphenazine. It is often used in bipolar disorder. eHealthMe is studying from 1,448 Trilafon users. Check the latest studies of Trilafon.

On Jul, 08, 2026

16 people who take Actonel and Trilafon together, and have interactions are studied.

What are the common drug interactions of Actonel and Trilafon, by gender? *:

female:

Hyperlipidaemia (presence of excess lipids in the blood)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Bone giant cell tumour (uncommon tumour of the bone)
Bone marrow oedema (inflammation that causes much than the needed fluid in a bone)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Deafness
Device failure
Disability
Dysphagia (a condition in which swallowing is difficult or painful)
Exostosis (formation of new bone on the surface of a bone)

male:

n/a

What are the common drug interactions of Actonel and Trilafon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Polyp colorectal
Psychotic disorder
Restlessness (not able to rest)
Suicidal ideation
Type 2 diabetes mellitus
Avulsion fracture (bone fracture)
Chest pain
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Fibromyalgia (a long-term condition which causes pain all over the body)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)

50-59:

Anaemia (lack of blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Deafness
Device failure
Disability
Dysphagia (a condition in which swallowing is difficult or painful)
Exostosis (formation of new bone on the surface of a bone)
Gingival disorder (gum disease)
Hyperlipidaemia (presence of excess lipids in the blood)

60+:

n/a

What are the existing conditions these people have? *

Sleep Disorder: 1 person, 6.25%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 6.25%
Depression: 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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