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Actos and Ciprodex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actos (pioglitazone hydrochloride) and Ciprodex (ciprofloxacin; dexamethasone). Common drug interactions include death among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Actos and Ciprodex. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Ciprodex?

Ciprodex has active ingredients of ciprofloxacin; dexamethasone. It is often used in otitis. eHealthMe is studying from 1,887 Ciprodex users. Check the latest studies of Ciprodex.

On Jul, 31, 2026

11 people who take Actos and Ciprodex together, and have interactions are studied.

Actos and Ciprodex drug interactions.

What are the common drug interactions of Actos and Ciprodex, by gender? *:

female:

  1. Death

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Death
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  7. Nephrogenic anaemia (anaemia due to kidney disease)
  8. Renal impairment (severely reduced kidney function)

What are the common drug interactions of Actos and Ciprodex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal injury (kidney injury)
  4. Death

60+:

  1. Chronic kidney disease
  2. Death
  3. Renal failure (kidney dysfunction)
  4. Renal impairment (severely reduced kidney function)
  5. Renal injury (kidney injury)

What are the existing conditions these people have? *

  1. Pain: 9 people, 81.82%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 72.73%
  3. Stress And Anxiety: 7 people, 63.64%
  4. Depression: 5 people, 45.45%
  5. High Blood Pressure: 5 people, 45.45%
  6. Blood Pressure Abnormal: 4 people, 36.36%
  7. Urinary Tract Infection: 3 people, 27.27%
  8. Irritable Bowel Syndrome: 3 people, 27.27%
  9. Cardiac Disorder: 3 people, 27.27%
  10. Diarrhea: 3 people, 27.27%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and Ciprodex?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Actos and Ciprodex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ciprodex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actos and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ciprodex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride and ciprofloxacin; dexamethasone (the active ingredients of Actos and Ciprodex, respectively), and Actos and Ciprodex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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