Actos and Haloperidol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actos (pioglitazone hydrochloride) and Haloperidol (haloperidol). Common drug interactions include abdominal discomfort among females and hypertension among males.

The phase IV clinical study analyzes what interactions people have when they take Actos and Haloperidol. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Haloperidol?

Haloperidol has active ingredients of haloperidol. It is often used in schizophrenia. eHealthMe is studying from 16,637 Haloperidol users. Check the latest studies of Haloperidol.



On Jul, 25, 2026

29 people who take Actos and Haloperidol together, and have interactions are studied.

Actos and Haloperidol drug interactions.

What are the common drug interactions of Actos and Haloperidol, by gender? *:

female:

  1. Abdominal discomfort
  2. Anaemia (lack of blood)
  3. Asthenia (weakness)
  4. Back pain
  5. Blood cholesterol increased
  6. Colon cancer
  7. Dementia (madness)
  8. Diplopia (double vision)
  9. Dry mouth
  10. Dyspnoea (difficult or laboured respiration)

male:

  1. Hypertension (high blood pressure)
  2. Back pain
  3. Hepatic neoplasm malignant (liver cancer)
  4. Obesity (having too much body fat)
  5. Oedema (fluid collection in tissue)
  6. Varices oesophageal (enlarged and swollen veins at the bottom of the oesophagus, near the stomach)
  7. Acute respiratory failure
  8. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  9. Chest pain
  10. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)

What are the common drug interactions of Actos and Haloperidol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acanthosis nigricans (skin disease-dark warlike patches in the body folds)
  2. Hyperglycaemia (high blood sugar)
  3. Obesity (having too much body fat)

20-29:

  1. Blood cholesterol increased
  2. Gestational diabetes (diabetes in pregnancy)
  3. Hypercholesterolaemia (high levels of cholesterol in the blood)
  4. Hyperglycaemia (high blood sugar)
  5. Hyperlipidaemia (presence of excess lipids in the blood)
  6. Neuropathy peripheral (surface nerve damage)
  7. Obesity (having too much body fat)

30-39:

  1. Gastric ulcer (stomach ulcer)
  2. Hepatic enzyme increased
  3. Hypertension (high blood pressure)
  4. Pneumonia

40-49:

  1. Diabetic neuropathy (neuropathic disorders that are associated with diabetes mellitus)
  2. Gastric ulcer (stomach ulcer)
  3. Hyperglycaemia (high blood sugar)
  4. Hypertension (high blood pressure)
  5. Pneumonia
  6. Weight increased
  7. Obesity (having too much body fat)
  8. Chest pain
  9. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  10. Dizziness

50-59:

  1. Back pain
  2. Blood cholesterol increased
  3. Hypertension (high blood pressure)
  4. Hypoglycaemia (deficiency of glucose in the bloodstream)
  5. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  6. Neuropathy peripheral (surface nerve damage)
  7. Arthralgia (joint pain)
  8. Anxiety
  9. Colon cancer
  10. Dementia (madness)

60+:

  1. Ascites (accumulation of fluid in the abdominal cavity)
  2. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  3. Oedema (fluid collection in tissue)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Abdominal discomfort
  6. Abdominal distension
  7. Acute respiratory failure
  8. Agitation (state of anxiety or nervous excitement)
  9. Alanine aminotransferase increased
  10. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)

What are the existing conditions these people have? *

  1. Depression: 10 people, 34.48%
  2. Sleep Disorder: 8 people, 27.59%
  3. Psychotic Disorder: 8 people, 27.59%
  4. Type 2 Diabetes: 7 people, 24.14%
  5. Stress And Anxiety: 5 people, 17.24%
  6. Bipolar Disorder (mood disorder): 4 people, 13.79%
  7. Pain: 4 people, 13.79%
  8. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 10.34%
  9. Dizziness: 3 people, 10.34%
  10. Swallowing Difficulty: 3 people, 10.34%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and Haloperidol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Actos and Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Actos:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Haloperidol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Actos and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Haloperidol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on pioglitazone hydrochloride and haloperidol (the active ingredients of Actos and Haloperidol, respectively), and Actos and Haloperidol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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