Actos and Nevanac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actos (pioglitazone hydrochloride) and Nevanac (nepafenac). Common drug interactions include eye irritation among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Actos and Nevanac. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Nevanac?

Nevanac has active ingredients of nepafenac. It is often used in cataract removal. eHealthMe is studying from 1,755 Nevanac users. Check the latest studies of Nevanac.

On Jul, 09, 2026

12 people who take Actos and Nevanac together, and have interactions are studied.

What are the common drug interactions of Actos and Nevanac, by gender? *:

female:

Eye irritation
Multiple injuries
Presyncope
Staphylococcal infection (an infection with staphylococcus bacteria)
Urinary retention (the inability to completely or partially empty the bladder)
Uveitis (inflammation of the uvea)
Back pain
Blood glucose increased
Chest discomfort
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)

male:

Death
Abdominal distension
Atrioventricular block second degree (heart block second degree)
Blood glucose increased
Bradycardia (abnormally slow heart action)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Cardiac arrest
Cardiac failure congestive
Cardiac valve disease (heart valve disease)
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)

What are the common drug interactions of Actos and Nevanac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Pancreatitis (inflammation of pancreas)
Weight decreased

40-49:

n/a

50-59:

Viral infection
White blood cell count increased
Abdominal pain
Back pain
Blindness unilateral
Blood glucose increased
Cataract (clouding of the lens inside the eye)
Corneal abrasion (loss of the surface of cornea)
Cough
Diarrhoea

60+:

Anxiety
Cardiac failure congestive
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Cough
Dizziness
Escherichia infection (bacterial infection by escherichia coli)
Eye irritation
Fatigue (feeling of tiredness)
Hyperhidrosis (abnormally increased sweating)
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
Pain: 2 people, 16.67%
Insomnia (sleeplessness): 2 people, 16.67%
Type 2 Diabetes: 2 people, 16.67%
Vitamin D Abnormal: 1 person, 8.33%
Depression: 1 person, 8.33%
Blood Pressure Abnormal: 1 person, 8.33%
Cardiac Disorder: 1 person, 8.33%
Cardiac Failure Congestive: 1 person, 8.33%
Chest Pain: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Actos and Nevanac?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously