Actos and Nuvaring drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Actos (pioglitazone hydrochloride) and Nuvaring (ethinyl estradiol; etonogestrel). Common drug interactions include pulmonary embolism among females.

The phase IV clinical study analyzes what interactions people have when they take Actos and Nuvaring. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Actos?

Actos has active ingredients of pioglitazone hydrochloride. It is often used in diabetes. eHealthMe is studying from 49,754 Actos users. Check the latest studies of Actos.

What is Nuvaring?

Nuvaring has active ingredients of ethinyl estradiol; etonogestrel. It is often used in birth control. eHealthMe is studying from 28,730 Nuvaring users. Check the latest studies of Nuvaring.

On Jul, 26, 2026

15 people who take Actos and Nuvaring together, and have interactions are studied.

What are the common drug interactions of Actos and Nuvaring, by gender? *:

female:

Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Coital bleeding (bleeding after sexual intercourse)
Injury
Lumbar radiculopathy (radicular pain in the low back and legs)
Nausea (feeling of having an urge to vomit)
Pharyngitis (inflammation of the pharynx, causing a sore throat)
Prothrombin time shortened
Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)

male:

n/a

What are the common drug interactions of Actos and Nuvaring, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Pulmonary embolism (blockage of the main artery of the lung)
Pulmonary hypertension (increase in blood pressure in the lung artery)
Prothrombin time shortened
Weight decreased
Abortion spontaneous (naturally occurring miscarriage)
Anaemia vitamin b12 deficiency
Aortic valve disease
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Blood uric acid
Cardiac disorder

40-49:

n/a

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 6 people, 40.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 13.33%
Thrombosis (formation of a blood clot inside a blood vessel): 1 person, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Menstruation Irregular: 1 person, 6.67%
Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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