Actrapid and Avastin drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Actrapid (insulin) and Avastin (bevacizumab). Common drug interactions include osteonecrosis of jaw among females and cerebellar syndrome among males.
The phase IV clinical study analyzes what interactions people have when they take Actrapid and Avastin. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Actrapid?
Actrapid has active ingredients of insulin. eHealthMe is studying from 4,864 Actrapid users. Check the latest studies of Actrapid.
What is Avastin?
Avastin has active ingredients of bevacizumab. It is often used in high blood cholesterol. eHealthMe is studying from 76,365 Avastin users. Check the latest studies of Avastin.
11 people who take Actrapid and Avastin together, and have interactions are studied.

What are the common drug interactions of Actrapid and Avastin, by gender? *:
female:
- Osteonecrosis of jaw (death of bone of jaw)
- Asthenia (weakness)
- Death
- Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
- Large intestine perforation (hole in large intestine)
- Lung infection
- Pleural effusion (water on the lungs)
- Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)
- Renal impairment (severely reduced kidney function)
- Anal fissure
male:
- Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Fall
- Leukopenia (less number of white blood cells in blood)
- Mesenteric vein thrombosis (blood clot in mesenteric vein)
- Pseudomonas test positive
- Rib fracture
- Urinary tract infection
- Venous thrombosis (blood clot (thrombus) that forms within a vein)
- Oral fungal infection
What are the common drug interactions of Actrapid and Avastin, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Oral fungal infection
60+:
- Osteonecrosis of jaw (death of bone of jaw)
- Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)
- Leukopenia (less number of white blood cells in blood)
- Lung infection
- Mesenteric vein thrombosis (blood clot in mesenteric vein)
- Pleural effusion (water on the lungs)
- Pneumoperitoneum (air or gas in the abdominal (peritoneal) cavity)
- Pseudomonas test positive
- Renal impairment (severely reduced kidney function)
- Rib fracture
What are the existing conditions these people have? *
- Diabetes: 4 people, 36.36%
- Breast Cancer: 3 people, 27.27%
- Urination - Excessive Volume: 1 person, 9.09%
- Rectal Cancer Metastatic (cancer of rectum spreads to other): 1 person, 9.09%
- Brain Neoplasm Malignant (brain cancer tumour): 1 person, 9.09%
- Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi): 1 person, 9.09%
- Coronary Heart Disease (narrowing or blockage of the coronary arteries): 1 person, 9.09%
- Disease Progression: 1 person, 9.09%
- Fluid Retention (an abnormal accumulation of fluid in the blood): 1 person, 9.09%
- Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Actrapid and Avastin?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Actrapid and Avastin:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Actrapid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Avastin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Actrapid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Avastin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on insulin and bevacizumab (the active ingredients of Actrapid and Avastin, respectively), and Actrapid and Avastin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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