Acular and Meloxicam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acular (ketorolac tromethamine) and Meloxicam (meloxicam). Common drug interactions include impaired healing among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Acular and Meloxicam. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Acular?

Acular has active ingredients of ketorolac tromethamine. eHealthMe is studying from 1,125 Acular users. Check the latest studies of Acular.

What is Meloxicam?

Meloxicam has active ingredients of meloxicam. It is often used in arthritis. eHealthMe is studying from 68,017 Meloxicam users. Check the latest studies of Meloxicam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

40 people who take Acular and Meloxicam together, and have interactions are studied.

What are the common drug interactions of Acular and Meloxicam, by gender? *:

female:

Impaired healing
Bone callus excessive (excessive bony deposit formed between and around the broken ends of bone fractures)
Fracture displacement
Metastatic neoplasm (spreadable cancer tumour)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Synovial cyst (cyst of joint filled with synovial fluid)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Pathological fracture (broken bone caused by disease)
Achlorhydria (absence of hydrochloric acid in stomach juice)

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Pain in extremity
Abdominal pain
Abdominal pain upper
Anaemia (lack of blood)
Arthralgia (joint pain)
Arthropathy
Atrioventricular block first degree (heart block first degree)
Back pain

What are the common drug interactions of Acular and Meloxicam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)

50-59:

Exostosis (formation of new bone on the surface of a bone)
Eye inflammation
Fatigue (feeling of tiredness)
Feeling hot
Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin)
Gait disturbance
Gingival bleeding (bleeding gums)
Glaucoma (increased fluid pressure in the eye with vision loss)
Glomerular filtration rate decreased
Gout (uric acid crystals building up in the body)

60+:

Chronic kidney disease
Fall
Bone callus excessive (excessive bony deposit formed between and around the broken ends of bone fractures)
Fracture displacement
Metastatic neoplasm (spreadable cancer tumour)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Synovial cyst (cyst of joint filled with synovial fluid)
Vertebral foraminal stenosis (narrowing of the intervertebral foramen)
Nephrogenic anaemia (anaemia due to kidney disease)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 13 people, 32.50%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 13 people, 32.50%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 27.50%
High Blood Cholesterol: 10 people, 25.00%
Pain: 8 people, 20.00%
Blood Pressure Abnormal: 6 people, 15.00%
Inflammation: 6 people, 15.00%
Infection: 6 people, 15.00%
Depression: 6 people, 15.00%
Herpes Virus Infection: 5 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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