Acyclovir sodium and Fentanyl citrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir sodium (acyclovir sodium) and Fentanyl citrate (fentanyl citrate). Common drug interactions include necrosis among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir sodium and Fentanyl citrate. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir sodium?

Acyclovir sodium has active ingredients of acyclovir sodium. eHealthMe is studying from 1,813 Acyclovir sodium users. Check the latest studies of Acyclovir sodium.

What is Fentanyl citrate?

Fentanyl citrate has active ingredients of fentanyl citrate. It is often used in pain. eHealthMe is studying from 21,294 Fentanyl citrate users. Check the latest studies of Fentanyl citrate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

14 people who take Acyclovir sodium and Fentanyl citrate together, and have interactions are studied.

Acyclovir sodium and Fentanyl citrate drug interactions.

What are the common drug interactions of Acyclovir Sodium and Fentanyl Citrate, by gender? *:

female:

Necrosis (the death of body tissue)
Pain in extremity
Anaemia (lack of blood)
Histiocytosis haematophagic
Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
Apnoeic attack
Arrhythmia (irregular heartbeat)
Blood pressure increased
Body temperature increased
Chills (felling of cold)

male:

Cardiac failure congestive
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Discomfort
Emotional distress
Hypophagia (reduced food intake)
Injury
Myelitis transverse (a neurological condition consisting of an inflammatory process of the spinal cord)
Osteonecrosis of jaw (death of bone of jaw)
Pleural fibrosis (formation of fibrous tissue in lung)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)

What are the common drug interactions of Acyclovir Sodium and Fentanyl Citrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Anaemia (lack of blood)
Circulatory collapse
Epstein-barr virus associated lymphoproliferative disorder (lymphocytes are produced in excessive quantities associated with epstein-barr virus)
Haemorrhage (bleeding)
Histiocytosis haematophagic
Hyperammonaemia
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
Infection
Oedema (fluid collection in tissue)

10-19:

n/a

20-29:

Abdominal pain upper
Acute graft versus host disease in skin (acute complication on skin following an allogeneic tissue/blood transplant)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Constipation
Hepatic enzyme increased
Histiocytosis haematophagic
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Rash
Serum ferritin increased
Varicella virus test positive

30-39:

n/a

40-49:

Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Atrophic vulvovaginitis (inflammation of the vulva)
Back pain
Bone disorder
Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
Bone pain
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)

50-59:

Cardiac failure congestive
Cauda equina syndrome (affecting the bundle of nerve roots)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Chronic respiratory failure
Constipation
Decreased appetite
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Drug dependence
Drug hypersensitivity

60+:

Dyspnoea (difficult or laboured respiration)
General physical health deterioration (weak health status)
Bone pain
Chest pain
Chills (felling of cold)
Creatinine renal clearance decreased
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Dehydration (dryness resulting from the removal of water)
Discomfort
Dysphagia (a condition in which swallowing is difficult or painful)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 42.86%
Urinary Tract Infection: 1 person, 7.14%
High Blood Cholesterol: 1 person, 7.14%
Bone Marrow Conditioning Regimen: 1 person, 7.14%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 1 person, 7.14%
Circulatory Collapse: 1 person, 7.14%
Constipation: 1 person, 7.14%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 7.14%
Depression: 1 person, 7.14%
Face Oedema (swelling of face): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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