Acyclovir sodium and Ibu drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir sodium (acyclovir sodium) and Ibu (ibuprofen). Common drug interactions include abdominal pain among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir sodium and Ibu. It is created by eHealthMe based on reports of 47 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir sodium?

Acyclovir sodium has active ingredients of acyclovir sodium. eHealthMe is studying from 1,813 Acyclovir sodium users. Check the latest studies of Acyclovir sodium.

What is Ibu?

Ibu has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 246,531 Ibu users. Check the latest studies of Ibu.



On Aug, 09, 2026

47 people who take Acyclovir sodium and Ibu together, and have interactions are studied.

Acyclovir sodium and Ibu drug interactions.

What are the common drug interactions of Acyclovir Sodium and Ibu, by gender? *:

female:

  1. Abdominal pain
  2. Anaemia (lack of blood)
  3. Bone pain
  4. Dehydration (dryness resulting from the removal of water)
  5. Depression
  6. Discomfort
  7. Gait disturbance
  8. Impaired healing
  9. Injury
  10. Spinal osteoarthritis (joint cartilage loss in spine)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Osteopenia (a condition where bone mineral density is lower than normal)
  4. Proteinuria (presence of protein in the urine)
  5. Renal failure (kidney dysfunction)
  6. Renal impairment (severely reduced kidney function)
  7. Weight increased
  8. Arthralgia (joint pain)
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  10. Atrioventricular block (heart block)

What are the common drug interactions of Acyclovir Sodium and Ibu, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Arthralgia (joint pain)
  2. Arthropathy
  3. Bone infarction (ischemic death of the cellular elements of the bone and marrow)
  4. Bone pain
  5. Decreased appetite
  6. Gait disturbance
  7. Impaired work ability
  8. Joint destruction (joint damage)
  9. Joint effusion (presence of extra fluid in joint covering)
  10. Linear iga disease (a rare, idiopathic or drug-induced autoimmune blistering disease of skin)

20-29:

  1. Blood creatinine increased
  2. Abdominal pain
  3. Abdominal pain upper
  4. Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

  1. Anxiety
  2. Bone density decreased
  3. Osteoporosis (bones weak and more likely to break)
  4. Renal failure (kidney dysfunction)
  5. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  6. Depression
  7. Fatigue (feeling of tiredness)
  8. Hand fracture
  9. Emotional distress
  10. Insomnia (sleeplessness)

50-59:

  1. Abscess oral (abscess in the mouth)
  2. Arthropathy
  3. Atelectasis (partial or complete collapse of the lung)
  4. Bone pain
  5. C-reactive protein increased
  6. Candidiasis (candidiasis or thrush is a fungal infection)
  7. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  8. Colonoscopy
  9. Compression fracture (fracture due to pressure caused by injury)
  10. Decreased interest

60+:

  1. Thrombocytopenia (decrease of platelets in blood)
  2. Dizziness
  3. Ascites (accumulation of fluid in the abdominal cavity)
  4. Bone disorder
  5. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  6. Breast cancer metastatic
  7. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  8. Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
  9. Constipation
  10. Death

What are the existing conditions these people have? *

  1. Hiv Infection: 9 people, 19.15%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 8 people, 17.02%
  3. Nausea (feeling of having an urge to vomit): 7 people, 14.89%
  4. Multiple Myeloma (cancer of the plasma cells): 7 people, 14.89%
  5. Depression: 6 people, 12.77%
  6. High Blood Pressure: 5 people, 10.64%
  7. Constipation: 5 people, 10.64%
  8. Headache (pain in head): 4 people, 8.51%
  9. Herpes Zoster: 4 people, 8.51%
  10. Stress And Anxiety: 4 people, 8.51%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acyclovir sodium and Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ibu:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ibu and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir sodium and ibuprofen (the active ingredients of Acyclovir sodium and Ibu, respectively), and Acyclovir sodium and Ibu (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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