Acyclovir sodium and Lortab drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir sodium (acyclovir sodium) and Lortab (acetaminophen; hydrocodone bitartrate). Common drug interactions include headache among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir sodium and Lortab. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir sodium?

Acyclovir sodium has active ingredients of acyclovir sodium. eHealthMe is studying from 1,813 Acyclovir sodium users. Check the latest studies of Acyclovir sodium.

What is Lortab?

Lortab has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 31,285 Lortab users. Check the latest studies of Lortab.



On Jul, 14, 2026

22 people who take Acyclovir sodium and Lortab together, and have interactions are studied.

Acyclovir sodium and Lortab drug interactions.

What are the common drug interactions of Acyclovir Sodium and Lortab, by gender? *:

female:

  1. Headache (pain in head)
  2. Intervertebral disc degeneration (spinal disc degeneration)
  3. Lung neoplasm (tumour of lung)
  4. Multiple myeloma (cancer of the plasma cells)
  5. Rectal haemorrhage (bleeding from anus)
  6. Synovial cyst (cyst of joint filled with synovial fluid)
  7. Anxiety
  8. Arthropathy
  9. Device related infection
  10. Impaired healing

male:

  1. Anaemia (lack of blood)
  2. Pneumonia
  3. Nausea (feeling of having an urge to vomit)
  4. Nephrolithiasis (calculi in the kidneys)
  5. Neuropathy peripheral (surface nerve damage)
  6. Osteonecrosis of jaw (death of bone of jaw)
  7. Osteopenia (a condition where bone mineral density is lower than normal)
  8. Osteoporosis (bones weak and more likely to break)
  9. Renal failure acute (rapid kidney dysfunction)
  10. Renal failure chronic (long lasting kidney dysfunction)

What are the common drug interactions of Acyclovir Sodium and Lortab, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Arthralgia (joint pain)
  2. Arthropathy
  3. Bone infarction (ischemic death of the cellular elements of the bone and marrow)
  4. Bone pain
  5. Decreased appetite
  6. Gait disturbance
  7. Headache (pain in head)
  8. Impaired work ability
  9. Joint destruction (joint damage)
  10. Joint effusion (presence of extra fluid in joint covering)

20-29:

n/a

30-39:

n/a

40-49:

  1. Pain in extremity
  2. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  3. Renal failure chronic (long lasting kidney dysfunction)
  4. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  5. Thrombocytopenia (decrease of platelets in blood)
  6. Bone pain
  7. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  8. Compression fracture (fracture due to pressure caused by injury)
  9. Constipation
  10. Dyspepsia (indigestion)

50-59:

n/a

60+:

  1. Anaemia (lack of blood)
  2. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  3. Weight decreased
  4. Lung neoplasm (tumour of lung)
  5. Staphylococcal infection (an infection with staphylococcus bacteria)
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  7. Arteriosclerosis (thickening and hardening of arteries)
  8. Arthropathy
  9. Bone atrophy (decrease in bone mass)
  10. Breast cancer metastatic

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 18.18%
  2. Metastases To Bone (cancer spreads to bone): 4 people, 18.18%
  3. Headache (pain in head): 2 people, 9.09%
  4. Aspergillosis (an infection caused by a fungus called aspergillus): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir sodium and Lortab?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acyclovir sodium and Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lortab:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir sodium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lortab and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir sodium and acetaminophen; hydrocodone bitartrate (the active ingredients of Acyclovir sodium and Lortab, respectively), and Acyclovir sodium and Lortab (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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