Acyclovir and Bumex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Bumex (bumetanide). Common drug interactions include pain among females and pancytopenia among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Bumex. It is created by eHealthMe based on reports of 97 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Bumex?

Bumex has active ingredients of bumetanide. It is often used in swelling. eHealthMe is studying from 9,210 Bumex users. Check the latest studies of Bumex.



On Jul, 15, 2026

97 people who take Acyclovir and Bumex together, and have interactions are studied.

Acyclovir and Bumex drug interactions.

What are the common drug interactions of Acyclovir and Bumex, by gender? *:

female:

  1. Pain
  2. Weight increased
  3. Asthenia (weakness)
  4. Chronic kidney disease
  5. Diarrhoea
  6. Abdominal pain
  7. Anxiety
  8. Confusional state
  9. Depression
  10. Dysuria (painful or difficult urination)

male:

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Confusional state
  4. Decreased appetite
  5. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  6. Dehydration (dryness resulting from the removal of water)
  7. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  8. Dizziness
  9. Drug intolerance (drug sensitivity)
  10. Drug toxicity

What are the common drug interactions of Acyclovir and Bumex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

  1. Acinetobacter infection (infection by group of bacteria commonly found in soil and water)
  2. Diarrhoea
  3. Diarrhoea haemorrhagic (bloody diarrhoea)
  4. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  5. Haematoma (collection of blood outside the blood vessels)
  6. Pleural effusion (water on the lungs)
  7. Pyrexia (fever)
  8. Septic shock (shock due to blood infection)
  9. Tooth abscess (pus formation in tooth)
  10. Extravasation (leakage of a fluid)

10-19:

  1. Body temperature increased
  2. Cardiac arrest
  3. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)

20-29:

n/a

30-39:

  1. Abdominal pain
  2. Anxiety
  3. Confusional state
  4. Constipation
  5. Depression
  6. Diplopia (double vision)
  7. Discomfort
  8. Drug dependence
  9. Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
  10. Dry mouth

40-49:

  1. Chronic kidney disease
  2. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

  1. Atrial flutter (an abnormal heart rhythm that occurs in the atria of the heart)
  2. Cardiac failure
  3. Cardiac failure congestive
  4. Chronic kidney disease
  5. Dyspnoea (difficult or laboured respiration)
  6. Erythema (redness of the skin)
  7. Fall
  8. Fatigue (feeling of tiredness)
  9. Fibromyalgia (a long-term condition which causes pain all over the body)
  10. Hypertension (high blood pressure)

60+:

  1. Diarrhoea
  2. Sepsis (a severe blood infection that can lead to organ failure and death)
  3. Confusional state
  4. Dizziness
  5. Electrolyte imbalance
  6. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Nausea (feeling of having an urge to vomit)
  9. Oedema peripheral (superficial swelling)
  10. Pulmonary oedema (fluid accumulation in the lungs)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 28 people, 28.87%
  2. Pain: 15 people, 15.46%
  3. Stress And Anxiety: 12 people, 12.37%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 12 people, 12.37%
  5. High Blood Pressure: 11 people, 11.34%
  6. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 7 people, 7.22%
  7. Nausea (feeling of having an urge to vomit): 6 people, 6.19%
  8. Lipids Increased (excess lipid in body): 6 people, 6.19%
  9. Platelet Aggregation Abnormal: 6 people, 6.19%
  10. Fungal Infection: 6 people, 6.19%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acyclovir and Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Bumex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Bumex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir and bumetanide (the active ingredients of Acyclovir and Bumex, respectively), and Acyclovir and Bumex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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