Acyclovir and Daraprim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Daraprim (pyrimethamine). Common drug interactions include thrombocytopenia among females and abdominal pain upper among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Daraprim. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Daraprim?

Daraprim has active ingredients of pyrimethamine. eHealthMe is studying from 788 Daraprim users. Check the latest studies of Daraprim.

On Jul, 26, 2026

20 people who take Acyclovir and Daraprim together, and have interactions are studied.

Acyclovir and Daraprim drug interactions.

What are the common drug interactions of Acyclovir and Daraprim, by gender? *:

female:

Thrombocytopenia (decrease of platelets in blood)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone cyst
Bone density decreased
Cerebral haemorrhage (bleeding within the brain)
Chronic kidney disease
Death
Depression

male:

Abdominal pain upper
Nausea (feeling of having an urge to vomit)
Pancreatitis (inflammation of pancreas)
Urinary tract obstruction
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blindness
Death
Difficulty in micturition (difficulty to urinate)
Dysuria (painful or difficult urination)
Fatigue (feeling of tiredness)

What are the common drug interactions of Acyclovir and Daraprim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Death
Abdominal pain upper
Calculus urinary (stone in urinary system)
Difficulty in micturition (difficulty to urinate)
Dysuria (painful or difficult urination)

40-49:

Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Bone cyst
Bone density decreased
Cerebral haemorrhage (bleeding within the brain)
Chronic kidney disease
Depression
Emotional distress
Kaposi's sarcoma (a tumour caused by human herpes virus)

50-59:

Abdominal pain upper
Back pain
Acute lymphocytic leukaemia recurrent (cancer in which the bone marrow makes too many lymphocytes-recurrent)
Blindness
Calculus urinary (stone in urinary system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Blood creatinine increased
Chest pain
Chills (felling of cold)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

60+:

n/a

What are the existing conditions these people have? *

Hiv Infection: 2 people, 10.00%
Nausea (feeling of having an urge to vomit): 2 people, 10.00%
Haematopoietic Stem Cell Mobilisation: 2 people, 10.00%
Vitamin B Complex Deficiency: 1 person, 5.00%
Anaemia (lack of blood): 1 person, 5.00%
Asthma: 1 person, 5.00%
Back Pain: 1 person, 5.00%
Bacterial Infection: 1 person, 5.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 5.00%
Constipation: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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