Acyclovir and Evoxac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Evoxac (cevimeline hydrochloride). Common drug interactions include diarrhoea among females and anaphylactic shock among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Evoxac. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Evoxac?

Evoxac has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 2,028 Evoxac users. Check the latest studies of Evoxac.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 14, 2026

20 people who take Acyclovir and Evoxac together, and have interactions are studied.

What are the common drug interactions of Acyclovir and Evoxac, by gender? *:

female:

Diarrhoea
Fatigue (feeling of tiredness)
Anxiety
Arrhythmia (irregular heartbeat)
Arthralgia (joint pain)
Aura
Death
Dyspnoea (difficult or laboured respiration)
Eye pain
Fall

male:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood cholesterol increased
Barrett's oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach)
Impaired healing
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Sepsis (a severe blood infection that can lead to organ failure and death)
Skin ulcer
Dyspnoea (difficult or laboured respiration)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Oxygen saturation decreased

What are the common drug interactions of Acyclovir and Evoxac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Blood cholesterol increased
Dyspnoea (difficult or laboured respiration)
Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
Oxygen saturation decreased
Sinusitis (inflammation of sinus)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tremor (trembling or shaking movements in one or more parts of your body)
Urinary tract infection
Adrenal insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids)

60+:

Diarrhoea
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Pneumonia fungal
Rash
Blood glucose decreased
Chest pain
Cystitis (inflammation of the wall of the bladder)
Pleuritic pain
Abdominal pain upper

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 25.00%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 25.00%
Drowsiness: 5 people, 25.00%
Multiple Myeloma (cancer of the plasma cells): 5 people, 25.00%
Migraine (headache): 4 people, 20.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Insomnia (sleeplessness): 3 people, 15.00%
Pain: 3 people, 15.00%
Dry Mouth: 3 people, 15.00%
Depression: 3 people, 15.00%

* Approximation only. Some reports may have incomplete information.

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