Acyclovir and Magnesium chloride drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Magnesium chloride (magnesium). Common drug interactions include white blood cell count decreased among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Magnesium chloride. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Magnesium chloride?

Magnesium chloride has active ingredients of magnesium. It is often used in hypomagnesemia. eHealthMe is studying from 631 Magnesium chloride users. Check the latest studies of Magnesium chloride.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 26, 2026

51 people who take Acyclovir and Magnesium chloride together, and have interactions are studied.

Acyclovir and Magnesium chloride drug interactions.

What are the common drug interactions of Acyclovir and Magnesium Chloride, by gender? *:

female:

  1. White blood cell count decreased
  2. Drug ineffective
  3. Neutropenia (an abnormally low number of neutrophils)
  4. Abdominal pain upper
  5. Vomiting
  6. Anaemia (lack of blood)
  7. Diarrhoea
  8. Dizziness
  9. Fatigue (feeling of tiredness)
  10. Skin exfoliation (removal of the oldest dead skin cells)

male:

  1. Diarrhoea
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Weight decreased
  4. Anaemia (lack of blood)
  5. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  6. Blood pressure increased
  7. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  8. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  9. Delayed sleep phase
  10. Exostosis (formation of new bone on the surface of a bone)

What are the common drug interactions of Acyclovir and Magnesium Chloride, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Diarrhoea
  2. Vomiting
  3. C-reactive protein increased
  4. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  5. Gastroenteritis (inflammation of stomach and intestine)
  6. Pyrexia (fever)
  7. Stomatitis (inflammation of mucous membrane of mouth)
  8. Weight decreased

20-29:

n/a

30-39:

  1. Abdominal pain upper
  2. Skin exfoliation (removal of the oldest dead skin cells)
  3. Abdominal pain
  4. Anaemia (lack of blood)
  5. Chest pain
  6. Duodenitis (inflammation of the duodenum)
  7. Eye inflammation
  8. Fatigue (feeling of tiredness)
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Muscle twitching

40-49:

  1. Blood pressure increased
  2. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  3. Delayed sleep phase
  4. Exostosis (formation of new bone on the surface of a bone)
  5. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  6. Hypercholesterolaemia (high levels of cholesterol in the blood)
  7. Nasal obstruction (blockage of nose)
  8. Nasal turbinate hypertrophy (nasal turbinates become enlarged)
  9. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  10. Rhinitis allergic (inflammation of the nasal airways due to allergy)

50-59:

  1. Abdominal distension
  2. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  3. Diarrhoea
  4. Flatulence (flatus expelled through the anus)
  5. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)

60+:

  1. White blood cell count decreased
  2. Febrile neutropenia (fever with reduced white blood cells)
  3. Abdominal pain upper
  4. Alanine aminotransferase increased
  5. Anaemia (lack of blood)
  6. Aspartate aminotransferase increased
  7. Asthenia (weakness)
  8. Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Cardiac failure

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 25 people, 49.02%
  2. Nausea (feeling of having an urge to vomit): 4 people, 7.84%
  3. Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 3 people, 5.88%
  4. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and Magnesium chloride?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acyclovir and Magnesium chloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Magnesium chloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Magnesium chloride and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on acyclovir and magnesium (the active ingredients of Acyclovir and Magnesium chloride, respectively), and Acyclovir and Magnesium chloride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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