Acyclovir and Pentacarinat drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Pentacarinat (pentamidine isethionate). Common drug interactions include renal tubular necrosis among females and drug intolerance among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Pentacarinat. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Pentacarinat?

Pentacarinat has active ingredients of pentamidine isethionate. eHealthMe is studying from 1,546 Pentacarinat users. Check the latest studies of Pentacarinat.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

42 people who take Acyclovir and Pentacarinat together, and have interactions are studied.

Acyclovir and Pentacarinat drug interactions.

What are the common drug interactions of Acyclovir and Pentacarinat, by gender? *:

female:

Renal tubular necrosis (death of kidney tubules)
Respiratory distress (difficulty in breathing)
Respiratory failure (inadequate gas exchange by the respiratory system)
Restrictive pulmonary disease (reduction in total lung capacity)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Speech disorder
Supraventricular extrasystoles (premature electrical impulse in the heart, generated above the level of the ventricle)
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Tricuspid valve incompetence (inefficient heart valve)
Urinary tract disorder

male:

Drug intolerance (drug sensitivity)
Disease progression
Inflammation
Nephropathy (damage to or disease of a kidney)
Chronic allograft nephropathy (failure of kidney transplant)
Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood creatinine increased
Cystoid macular oedema (fluid accumulation after cataract surgery)
Idiosyncratic drug reaction (unusual effect of the medication)
Kidney transplant rejection

What are the common drug interactions of Acyclovir and Pentacarinat, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Neutropenia (an abnormally low number of neutrophils)
Pyrexia (fever)
Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
Inflammation
Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
Tumour pain

50-59:

Haematotoxicity (toxins that destroy red blood cells)
Antiphospholipid syndrome (disorder that manifests clinically as recurrent venous or arterial thrombosis and/or fetal loss)
Anxiety disorder
Colitis ulcerative (inflammation of colon with ulcer)
Complex regional pain syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet))
Coombs positive haemolytic anaemia
Depression
Drug hypersensitivity
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Erysipelas (bacterial skin infection)

60+:

Drug intolerance (drug sensitivity)
Interstitial lung disease
Lung disorder (lung disease)
Nephropathy (damage to or disease of a kidney)
Pyrexia (fever)
Chronic allograft nephropathy (failure of kidney transplant)
Haematotoxicity (toxins that destroy red blood cells)
Bile duct stenosis (abnormal narrowing of the common bile duct)
Blood creatinine increased
Cardiac failure congestive

What are the existing conditions these people have? *

Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 23.81%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 8 people, 19.05%
Multiple Myeloma (cancer of the plasma cells): 7 people, 16.67%
Bone Disorder: 4 people, 9.52%
Constipation: 3 people, 7.14%
Central Nervous System Lymphoma (cancer of central nervous system forms in lymph tissue): 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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