Acyclovir and Pyridium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Pyridium (phenazopyridine hydrochloride). Common drug interactions include pain among females.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Pyridium. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Pyridium?

Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,841 Pyridium users. Check the latest studies of Pyridium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 31, 2026

19 people who take Acyclovir and Pyridium together, and have interactions are studied.

Acyclovir and Pyridium drug interactions.

What are the common drug interactions of Acyclovir and Pyridium, by gender? *:

female:

Pain
Anxiety
Nausea (feeling of having an urge to vomit)
Osteoporosis (bones weak and more likely to break)
Rash
Swelling
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Arthralgia (joint pain)

male:

n/a

What are the common drug interactions of Acyclovir and Pyridium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Metastases to spine (cancer spreads to spine)
Metastases to thorax (cancer spreads to thorax)
Micturition urgency (urgency to pass the urine)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nausea (feeling of having an urge to vomit)
Neck pain
Neoplasm progression (growth of tumour)
Oral pain

40-49:

n/a

50-59:

Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Lymphoma (cancer that begins in immune system cells)
Platelet count decreased
Vaginal haemorrhage (vaginal bleeding)
White blood cell count increased
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)
Retinal dystrophy (progressive weakness and wasting of the retina)

60+:

Death
Dry skin
Swelling
Urticaria (rash of round, red welts on the skin that itch intensely)
Wheezing (a high-pitched whistling sound made while you breath)
Breast cancer
Hypertension (high blood pressure)
Nausea (feeling of having an urge to vomit)
Oxygen saturation decreased
Thrombosis (formation of a blood clot inside a blood vessel)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 5 people, 26.32%
Nausea (feeling of having an urge to vomit): 4 people, 21.05%
Asthma: 3 people, 15.79%
Pain: 3 people, 15.79%
Hyperglycemia (high blood sugar): 2 people, 10.53%
Immunodeficiency Common Variable: 2 people, 10.53%
Constipation: 2 people, 10.53%
Gastric Ulcer (stomach ulcer): 2 people, 10.53%
Oropharyngeal Pain: 2 people, 10.53%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 2 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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