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Acyclovir and Zicam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Acyclovir (acyclovir) and Zicam (zinc gluconate). Common drug interactions include vomiting among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Acyclovir and Zicam. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Acyclovir?

Acyclovir has active ingredients of acyclovir. It is often used in herpes simplex. eHealthMe is studying from 54,961 Acyclovir users. Check the latest studies of Acyclovir.

What is Zicam?

Zicam has active ingredients of zinc gluconate. It is often used in herpes labialis (oral herpes simplex). eHealthMe is studying from 5,298 Zicam users. Check the latest studies of Zicam.

On Jul, 27, 2026

11 people who take Acyclovir and Zicam together, and have interactions are studied.

Acyclovir and Zicam drug interactions.

What are the common drug interactions of Acyclovir and Zicam, by gender? *:

female:

  1. Vomiting
  2. Blood pressure increased
  3. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  4. Headache (pain in head)
  5. Infusion related reaction
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Vertigo
  8. Ageusia (loss of taste functions of the tongue)
  9. Anosmia (partial or complete loss of the sense of smell)
  10. Abdominal pain upper

male:

  1. Dizziness
  2. Head discomfort
  3. Somnolence (a state of near-sleep, a strong desire for sleep)

What are the common drug interactions of Acyclovir and Zicam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Ageusia (loss of taste functions of the tongue)
  2. Anosmia (partial or complete loss of the sense of smell)

40-49:

  1. Vertigo

50-59:

  1. Ageusia (loss of taste functions of the tongue)
  2. Dizziness
  3. Head discomfort
  4. Somnolence (a state of near-sleep, a strong desire for sleep)

60+:

  1. Ageusia (loss of taste functions of the tongue)
  2. Anosmia (partial or complete loss of the sense of smell)

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 18.18%
  2. Breast Cancer: 2 people, 18.18%
  3. Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
  4. Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Acyclovir and Zicam?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Acyclovir and Zicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Acyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zicam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Acyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zicam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on acyclovir and zinc gluconate (the active ingredients of Acyclovir and Zicam, respectively), and Acyclovir and Zicam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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