Adalat cc and Reglan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Adalat cc (nifedipine) and Reglan (metoclopramide hydrochloride). Common drug interactions include pulmonary oedema among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Adalat cc and Reglan. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Adalat cc?

Adalat cc has active ingredients of nifedipine. It is often used in high blood pressure. eHealthMe is studying from 5,019 Adalat cc users. Check the latest studies of Adalat cc.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.



On Aug, 01, 2026

18 people who take Adalat cc and Reglan together, and have interactions are studied.

Adalat cc and Reglan drug interactions.

What are the common drug interactions of Adalat Cc and Reglan, by gender? *:

female:

  1. Pulmonary oedema (fluid accumulation in the lungs)
  2. Renal failure chronic (long lasting kidney dysfunction)
  3. Respiratory distress (difficulty in breathing)
  4. Retinopathy diabetic (acute damage to the retina of the eye due to diabetes)
  5. Bankruptcy
  6. Compulsive hoarding (unwillingness to discard large quantities of objects that cover the living areas)
  7. Compulsive sexual behaviour (unable to manage his/her sexual behaviour)
  8. Compulsive shopping
  9. Emotional distress
  10. Fluid retention (an abnormal accumulation of fluid in the blood)

male:

  1. Fatigue (feeling of tiredness)
  2. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  3. Hepatocellular damage (liver damage)
  4. Hepatomegaly (abnormal enlargement of the liver)
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Hyperthermia malignant (disease passed down through families that causes a fast rise in body temperature (fever) and severe muscle contractions)
  8. Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
  9. Pain
  10. Pneumonia

What are the common drug interactions of Adalat Cc and Reglan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  2. Atrioventricular block complete (heart block complete)
  3. Blood triglycerides increased
  4. Bradycardia (abnormally slow heart action)
  5. Cardiac arrest
  6. Cardiogenic shock (inadequate circulation of blood)
  7. Electrocardiogram qt prolonged
  8. Hepatic steatosis (fatty liver disease)
  9. Hepatitis (inflammation of the liver)
  10. Hepatocellular damage (liver damage)

40-49:

  1. Blood bilirubin increased
  2. Cholecystitis (infection of gallbladder)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Constipation
  5. Contusion (a type of hematoma of tissue in which capillaries)
  6. Decreased appetite
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Dysgeusia (disorder of the sense of taste)
  9. Fatigue (feeling of tiredness)
  10. Hair colour changes

50-59:

  1. Visual disturbance

60+:

  1. Drug hypersensitivity
  2. Fatigue (feeling of tiredness)
  3. Fluid retention (an abnormal accumulation of fluid in the blood)
  4. Hirsutism (abnormal growth of hair on a person's face and body, esp. on a woman)
  5. Pain

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 16.67%
  2. Pain: 3 people, 16.67%
  3. Stress And Anxiety: 2 people, 11.11%
  4. Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 2 people, 11.11%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 2 people, 11.11%
  6. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 11.11%
  7. Post-Traumatic Stress Disorder: 2 people, 11.11%
  8. Insomnia (sleeplessness): 2 people, 11.11%
  9. Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 11.11%
  10. Stable Angina (a constant chest pain): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Adalat cc and Reglan?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Adalat cc and Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Adalat cc:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adalat cc and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Reglan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on nifedipine and metoclopramide hydrochloride (the active ingredients of Adalat cc and Reglan, respectively), and Adalat cc and Reglan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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